About: Crinane Alkaloids of the Amaryllidaceae with Cytotoxic Effects in Human Cervical Adenocarcinoma (HeLa) Cells     Goto   Sponge   NotDistinct   Permalink

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  • The family Amaryllidaceae has a long history of usage in the traditional medicinal practices of the indigenous peoples of South Africa, with three of its species known to be used for cancer treatment. Furthermore, the Amaryllidaceae is widely recognized for its unique alkaloid constituents, several of which exhibit potent and selective cytotoxic activities. In this study, several crinane alkaloids derived from local Amaryllidaceae species were examined for cytotoxic effects against the human cervical adenocarcinoma cell line, of which distichamine was the most potent (IC50 2.2 mu M).
  • The family Amaryllidaceae has a long history of usage in the traditional medicinal practices of the indigenous peoples of South Africa, with three of its species known to be used for cancer treatment. Furthermore, the Amaryllidaceae is widely recognized for its unique alkaloid constituents, several of which exhibit potent and selective cytotoxic activities. In this study, several crinane alkaloids derived from local Amaryllidaceae species were examined for cytotoxic effects against the human cervical adenocarcinoma cell line, of which distichamine was the most potent (IC50 2.2 mu M). (en)
Title
  • Crinane Alkaloids of the Amaryllidaceae with Cytotoxic Effects in Human Cervical Adenocarcinoma (HeLa) Cells
  • Crinane Alkaloids of the Amaryllidaceae with Cytotoxic Effects in Human Cervical Adenocarcinoma (HeLa) Cells (en)
skos:prefLabel
  • Crinane Alkaloids of the Amaryllidaceae with Cytotoxic Effects in Human Cervical Adenocarcinoma (HeLa) Cells
  • Crinane Alkaloids of the Amaryllidaceae with Cytotoxic Effects in Human Cervical Adenocarcinoma (HeLa) Cells (en)
skos:notation
  • RIV/61389030:_____/14:00429594!RIV15-AV0-61389030
http://linked.open...avai/riv/aktivita
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  • I, P(LO1204)
http://linked.open...iv/cisloPeriodika
  • 4
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http://linked.open...aciTvurceVysledku
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  • 9183
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  • RIV/61389030:_____/14:00429594
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Alkaloid; Amaryllidaceae; Apoptosis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [DACDC20BF321]
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  • Natural Product Communications
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  • 9
http://linked.open...iv/tvurceVysledku
  • Strnad, Miroslav
  • van Staden, J.
  • Bastida, J.
  • Nair, J. J.
  • Rárová, L.
  • Cheesman, L.
http://linked.open...ain/vavai/riv/wos
  • 000335083500006
issn
  • 1934-578X
number of pages
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