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  • The effect of compression on Lactobacillus acidophilus was discussed. Their process includes the growth of bacteria, formulation, freeze drying, and compression to 'encapsulate' cells. Cell viability remains above 90% with compression pressures of 60 MPa, though decreases strongly after application of 90 MPa. Cell viability has been lower for thicker coatings due to a higher resistance to rehydration. Overall, the total release time has varied from 5 to 9 hours, implying that this system could avoid cell release in the stomach and small intestines. Therefore, targeted cell delivery to the low intestines seems possible.
  • The effect of compression on Lactobacillus acidophilus was discussed. Their process includes the growth of bacteria, formulation, freeze drying, and compression to 'encapsulate' cells. Cell viability remains above 90% with compression pressures of 60 MPa, though decreases strongly after application of 90 MPa. Cell viability has been lower for thicker coatings due to a higher resistance to rehydration. Overall, the total release time has varied from 5 to 9 hours, implying that this system could avoid cell release in the stomach and small intestines. Therefore, targeted cell delivery to the low intestines seems possible. (en)
Title
  • Cell Physiology and Interactions of Biomaterials and Matrices.
  • Cell Physiology and Interactions of Biomaterials and Matrices. (en)
skos:prefLabel
  • Cell Physiology and Interactions of Biomaterials and Matrices.
  • Cell Physiology and Interactions of Biomaterials and Matrices. (en)
skos:notation
  • RIV/61389030:_____/03:56033047!RIV/2004/AV0/A56004/N
http://linked.open.../vavai/riv/strany
  • 193;197
http://linked.open...avai/riv/aktivita
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  • P(OC 840.20), Z(AV0Z5038910)
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 600508
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  • RIV/61389030:_____/03:56033047
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  • Biomaterials; Cell physiology; Encapsulation (en)
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  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [C3638A38E625]
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  • Polymer News
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 28
http://linked.open...iv/tvurceVysledku
  • Vaňková, Radomíra
  • Hunkeler, D.
http://linked.open...n/vavai/riv/zamer
issn
  • 0032-3918
number of pages
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