About: Influence of surface-modified maghemite nanoparticles on in vitro survival of human stem cells

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Surface-modified maghemite (γ-Fe2O3) nanoparticles were obtained by using a conventional precipitation method and coated with D-mannose and poly(N,N-dimethylacrylamide). Both the initial and the modified particles were characterized by transmission electron microscopy and dynamic light scattering with regard to morphology, particle size and polydispersity. In vitro survival of human stem cells was then investigated by using the methyl thiazolyl tetrazolium (MTT) assay, which showed that D-mannose- and poly(N,N-dimethylacrylamide)-coated γ-Fe2O3 particles exhibit much lower level of cytotoxicity than the non-coated γ-Fe2O3. Surface-modified maghemite (γ-Fe2O3) nanoparticles were obtained by using a conventional precipitation method and coated with D-mannose and poly(N,N-dimethylacrylamide). Both the initial and the modified particles were characterized by transmission electron microscopy and dynamic light scattering with regard to morphology, particle size and polydispersity. In vitro survival of human stem cells was then investigated by using the methyl thiazolyl tetrazolium (MTT) assay, which showed that D-mannose- and poly(N,N-dimethylacrylamide)-coated γ-Fe2O3 particles exhibit much lower level of cytotoxicity than the non-coated γ-Fe2O3. (en)
Title	Influence of surface-modified maghemite nanoparticles on in vitro survival of human stem cells Influence of surface-modified maghemite nanoparticles on in vitro survival of human stem cells (en)
skos:prefLabel	Influence of surface-modified maghemite nanoparticles on in vitro survival of human stem cells Influence of surface-modified maghemite nanoparticles on in vitro survival of human stem cells (en)
skos:notation	RIV/61389013:_____/14:00433566!RIV15-AV0-61389013
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(EE2.3.30.0029), P(LH14318)
http://linked.open...iv/cisloPeriodika	8 October
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Horák, Daniel Babič, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav makromolekulární chemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	21632
http://linked.open...ai/riv/idVysledku	RIV/61389013:_____/14:00433566
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	maghemite; magnetic; MTT assay (en)
http://linked.open.../riv/klicoveSlovo	maghemite MTT assay magnetic
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[0BE93D21D2B6]
http://linked.open...i/riv/nazevZdroje	Beilstein Journal of Nanotechnology
http://linked.open...in/vavai/riv/obor	CD
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Synthesis of polymer-coated magnetic nanoparticles for biomedicine BIOPOL: BIOpolymer POstdoc Laboratory and educative center
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	5
http://linked.open...iv/tvurceVysledku	Horák, Daniel Babič, Michal Grypych, O. A. Kolomiets, Y. N. Lukash, L. L. Ruban, T. A. Shpylova, S. P.
http://linked.open...ain/vavai/riv/wos	000344115100001
issn	2190-4286
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.3762/bjnano.5.183

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