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Description
| - We describe a new biopolymer-based nanofibrous material possibly suitable for tissue engineering prepared by an environment-friendly organic solvent-free method. Glycogen, a biodegradable hyperbranched D-glucose polymer, comes from renewable resources and is normally present in man. It forms nanofibres by simple freeze-drying from aqueous solutions with concentration less than 0.5%. However, the architecture of the freeze-dried material depends on the starting biopolymer concentration within the tested range 0.1–5 wt%; in particular higher concentrations produce porous sponge-like structures with communicating pores. Because of the solubility of glycogen in water, nanofibres were modified by solvent-free grafting biodegradable poly(ethyl cyanoacrylate) from vapor phase. Exposing glycogen nanofibres to vapors of ethyl cyanoacrylate only slightly changed the material architecture while producing a water-insoluble biodegradable material with glycogen-to-poly(ethyl cyanoacrylate) ratio depending on the polymerization time. The material was proven to be hydrolytically degradable over the course of several months.
- We describe a new biopolymer-based nanofibrous material possibly suitable for tissue engineering prepared by an environment-friendly organic solvent-free method. Glycogen, a biodegradable hyperbranched D-glucose polymer, comes from renewable resources and is normally present in man. It forms nanofibres by simple freeze-drying from aqueous solutions with concentration less than 0.5%. However, the architecture of the freeze-dried material depends on the starting biopolymer concentration within the tested range 0.1–5 wt%; in particular higher concentrations produce porous sponge-like structures with communicating pores. Because of the solubility of glycogen in water, nanofibres were modified by solvent-free grafting biodegradable poly(ethyl cyanoacrylate) from vapor phase. Exposing glycogen nanofibres to vapors of ethyl cyanoacrylate only slightly changed the material architecture while producing a water-insoluble biodegradable material with glycogen-to-poly(ethyl cyanoacrylate) ratio depending on the polymerization time. The material was proven to be hydrolytically degradable over the course of several months. (en)
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Title
| - Biopolymer-based degradable nanofibres from renewable resources produced by freeze-drying
- Biopolymer-based degradable nanofibres from renewable resources produced by freeze-drying (en)
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skos:prefLabel
| - Biopolymer-based degradable nanofibres from renewable resources produced by freeze-drying
- Biopolymer-based degradable nanofibres from renewable resources produced by freeze-drying (en)
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skos:notation
| - RIV/61389013:_____/13:00394941!RIV14-GA0-61389013
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http://linked.open...avai/predkladatel
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - I, P(GA202/09/2078), P(GAP108/10/1560)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61389013:_____/13:00394941
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - glycogen; nanofibres; poly(ethyl cyanoacrylate) (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hrubý, Martin
- Přádný, Martin
- Vetrík, Miroslav
- Štěpánek, Petr
- Šlouf, Miroslav
- Kobera, Libor
- Pospíšilová, Aneta
- Rabyk, Mariia
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
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