About: Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	N-(2-Hydroxypropyl)methacrylamide polymer precursors (pHPMA) with very narrow distribution of molecular weights and polymer chain terminating in a single reactive group have big potential in the synthesis of various polymer drug and gene delivery systems. This paper shows that pHPMA can be prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization; the pHPMAs prepared by RAFT polymerization conducted to high conversions contained at the α-end of the polymer chain a single functional group originated from both, the chain transfer agent (CTA) and initiator (INI) in ratio depending on polymerization conditions. The well-defined monofunctional pHPMAs with narrow molecular weight distribution and with single reactive group situated at the α-polymer chain end can be prepared in one step by RAFT polymerization initiated by the tailor-made CTA and INI, both containing the same functional group in their structure. Synthesis of pHPMAs terminating in various reactive groups (azide, propargyl, thiazolidin-2-thione, amino, hydrazide) was also described. N-(2-Hydroxypropyl)methacrylamide polymer precursors (pHPMA) with very narrow distribution of molecular weights and polymer chain terminating in a single reactive group have big potential in the synthesis of various polymer drug and gene delivery systems. This paper shows that pHPMA can be prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization; the pHPMAs prepared by RAFT polymerization conducted to high conversions contained at the α-end of the polymer chain a single functional group originated from both, the chain transfer agent (CTA) and initiator (INI) in ratio depending on polymerization conditions. The well-defined monofunctional pHPMAs with narrow molecular weight distribution and with single reactive group situated at the α-polymer chain end can be prepared in one step by RAFT polymerization initiated by the tailor-made CTA and INI, both containing the same functional group in their structure. Synthesis of pHPMAs terminating in various reactive groups (azide, propargyl, thiazolidin-2-thione, amino, hydrazide) was also described. (en)
Title	Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization (en)
skos:prefLabel	Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization (en)
skos:notation	RIV/61389013:_____/13:00391498!RIV14-MSM-61389013
http://linked.open...avai/predkladatel	Ústav makromolekulární chemie AV ČR, v. v. i.
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(EE2.3.30.0029), P(GAP301/12/1254)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Strohalm, Jiří Ulbrich, Karel Etrych, Tomáš Šubr, Vladimír Kostka, Libor
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav makromolekulární chemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	109558
http://linked.open...ai/riv/idVysledku	RIV/61389013:_____/13:00391498
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	RAFT polymerization; N-(2-hydroxypropyl)methacrylamide; semitelechelic polymers (en)
http://linked.open.../riv/klicoveSlovo	N-(2-hydroxypropyl)methacrylamide RAFT polymerization semitelechelic polymers
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[25D627792AE1]
http://linked.open...i/riv/nazevZdroje	Macromolecules
http://linked.open...in/vavai/riv/obor	CD
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Overcoming Natural and Multidrug Resistance by Tumor-Selective Delivery of ABC Transporter/Bcl-2 Inhibitors or Therapeutic Gene under PEG-3 Promoter BIOPOL: BIOpolymer POstdoc Laboratory and educative center
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	46
http://linked.open...iv/tvurceVysledku	Etrych, Tomáš Strohalm, Jiří Ulbrich, Karel Šubr, Vladimír Kostka, Libor
http://linked.open...ain/vavai/riv/wos	000316847500007
issn	0024-9297
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1021/ma400042u

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 41 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software