About: Method of cultivation of human mesenchymal stem cells, particularly for the treatment of non-healing fractures, and bioreactor for carrying out this cultivation method

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About: Method of cultivation of human mesenchymal stem cells, particularly for the treatment of non-healing fractures, and bioreactor for carrying out this cultivation method Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20110720&DB=EPODOC&locale=en_EP&CC=EP&NR=1999250B1&KC=B1
Description	The invention relates to novel method of cultivation of mesenchymal stem cells, wherein after aseptic separation of mononuclear cells from the marrow blood, the said cells are seeded in low density into sterile plastic cultivation vessels and cultivated for about one to three weeks in CellGroTM Hematopoietic Stem cell Medium, certified for clinical use, with addition of 10% human serum and supplements, wherein the supplements are added at least once in the course of cultivation, without removal of hematopoietic cells and without medium exchange during the cultivation procedure, without any interference with the closed cultivation system, under standard conditions for the cultivation of tissue culture. The invention relates to novel method of cultivation of mesenchymal stem cells, wherein after aseptic separation of mononuclear cells from the marrow blood, the said cells are seeded in low density into sterile plastic cultivation vessels and cultivated for about one to three weeks in CellGroTM Hematopoietic Stem cell Medium, certified for clinical use, with addition of 10% human serum and supplements, wherein the supplements are added at least once in the course of cultivation, without removal of hematopoietic cells and without medium exchange during the cultivation procedure, without any interference with the closed cultivation system, under standard conditions for the cultivation of tissue culture. (en)
Title	Method of cultivation of human mesenchymal stem cells, particularly for the treatment of non-healing fractures, and bioreactor for carrying out this cultivation method Method of cultivation of human mesenchymal stem cells, particularly for the treatment of non-healing fractures, and bioreactor for carrying out this cultivation method (en)
skos:prefLabel	Method of cultivation of human mesenchymal stem cells, particularly for the treatment of non-healing fractures, and bioreactor for carrying out this cultivation method Method of cultivation of human mesenchymal stem cells, particularly for the treatment of non-healing fractures, and bioreactor for carrying out this cultivation method (en)
skos:notation	RIV/61389013:_____/11:00361674!RIV12-MZ0-61389013
http://linked.open...avai/predkladatel	Ústav makromolekulární chemie AV ČR, v. v. i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ND7448), Z(AV0Z40500505)
http://linked.open...cisloPatentuVzoru	EP1999250
http://linked.open...eleniPatentuVzoru	2011-07-20 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Rypáček, František Mulinková, Katarína
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav makromolekulární chemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	211756
http://linked.open...ai/riv/idVysledku	RIV/61389013:_____/11:00361674
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mesenchymal stem cells; cultivation; bone-fracture treatment (en)
http://linked.open.../riv/klicoveSlovo	cultivation bone-fracture treatment mesenchymal stem cells
http://linked.open...ontrolniKodProRIV	[C926D832630E]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	Munich, The Hague, Berlin, Vienna, Brussels
http://linked.open...atelePatentuVzoru	Evropský patentový úřad
http://linked.open...in/vavai/riv/obor	FJ
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Use of mesenchymal stem cells in reconstruction orthopaedics surgery
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Trč, T. Pytlík, R. Rypáček, František Hofman, P. Klener, P. Kobylka, P. Mulinková, Katarína Soukup, T. Stehlík, D.
http://linked.open...mniOchranaPatentu	A - EPO (Evropský patentový úřad)
http://linked.open...avai/riv/vlastnik	Univerzita Karlova v Praze - Ústav hematologie a krevní transfuze - Ústav makromolekulární chemie AV ČR, v. v. i.
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	A - Pouze udělený nebo využívaný pouze vlastníkem
http://linked.open...n/vavai/riv/zamer	Progresivní makromolekulární materiály a supramolekulární systémy: syntéza a studium vlastností, jevů a možností využití pro speciální aplikace a moderní technologie
http://linked.open...stnikPatentuVzoru	Univerzita Karlova v Praze - Ústav hematologie a krevní transfuze - Ústav makromolekulární chemie AV ČR, v. v. i.
is http://linked.open...avai/riv/vysledek of	Method of cultivation of human mesenchymal stem cells, particularly for the treatment of non-healing fractures, and bioreactor for carrying out this cultivation method Method of cultivation of human mesenchymal stem cells, particularly for the treatment of non-healing fractures, and bioreactor for carrying out this cultivation method

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