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Description
  • The effect of chemical composition of high-molecular-weight poly(L-lysine) cationic graft copolymers with short poly[N-(2-hydroxypropyl)methacrylamide] grafts on formation and stability of polyelectrolyte complexes with oligonucleotides and model oligomers was tested by light scattering methods as a novel synthetic vector suitable for gene therapy applications. Polyanion exchange reactions were also studied under physiological conditions.
  • The effect of chemical composition of high-molecular-weight poly(L-lysine) cationic graft copolymers with short poly[N-(2-hydroxypropyl)methacrylamide] grafts on formation and stability of polyelectrolyte complexes with oligonucleotides and model oligomers was tested by light scattering methods as a novel synthetic vector suitable for gene therapy applications. Polyanion exchange reactions were also studied under physiological conditions. (en)
Title
  • Cationic graft copolymers as carriers for delivery of antisense-oligonucleotides.
  • Cationic graft copolymers as carriers for delivery of antisense-oligonucleotides. (en)
skos:prefLabel
  • Cationic graft copolymers as carriers for delivery of antisense-oligonucleotides.
  • Cationic graft copolymers as carriers for delivery of antisense-oligonucleotides. (en)
skos:notation
  • RIV/61389013:_____/03:55033092!RIV/2004/AV0/A55004/N
http://linked.open.../vavai/riv/strany
  • 425;435
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(IAA1050101), P(IAA1050201), P(ME 362), Z(AV0Z4050913)
http://linked.open...iv/cisloPeriodika
  • 8
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 600457
http://linked.open...ai/riv/idVysledku
  • RIV/61389013:_____/03:55033092
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • drug delivery system; graft copolymers; light scattering (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [58C62AA53C16]
http://linked.open...i/riv/nazevZdroje
  • Macromolecular Bioscience
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 3
http://linked.open...iv/tvurceVysledku
  • Ulbrich, Karel
  • Koňák, Čestmír
  • Dautzenberg, H.
  • Reschel, Tomáš
  • Zintchenko, A.
http://linked.open...n/vavai/riv/zamer
issn
  • 1616-5187
number of pages
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