About: Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Publikovaná data pro přežití buněk V79 ozářených protony o energii 0.5-5MeV (7–40 keV/microm) byly analyzovány detailním radiobiologickým modelem s cílem odhadnout výtěžky letálních poškození ve stopě záření. Byly studovány jejich korelace s distribucemi deponované energie, koncentrace radikálů a výtěžky specifických typů poškození DNA. Zjištěné korelace ukazují možná poškození DNA letálních pro buňku a počáteční fyzikální a chemické procesy vedoucí k těmto poškozením. (cs) Published survival data of V79 cells irradiated by 0.5–5.0 MeV (7–40 keV=mm) protons have been analyzed with a detailed radiobiological model to estimate the per-track yields of lethal lesions. Their correlations with distribution patterns of deposited energy, radical concentrations and with the yields of specific classes of DNA damage have been studied. The observed correlations indicate a potential interpretation of DNA damage lethal for the cell and the initial physical and chemical processes leasing to such damage. Published survival data of V79 cells irradiated by 0.5–5.0 MeV (7–40 keV=mm) protons have been analyzed with a detailed radiobiological model to estimate the per-track yields of lethal lesions. Their correlations with distribution patterns of deposited energy, radical concentrations and with the yields of specific classes of DNA damage have been studied. The observed correlations indicate a potential interpretation of DNA damage lethal for the cell and the initial physical and chemical processes leasing to such damage. (en)
Title	Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage (en) Letální poškození buněk V79 ozářených nízkoenergetickými protony a jejich korelace s distribucemi deponované energie, koncentrace radikálů a poškození DNA (cs)
skos:prefLabel	Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage (en) Letální poškození buněk V79 ozářených nízkoenergetickými protony a jejich korelace s distribucemi deponované energie, koncentrace radikálů a poškození DNA (cs)
skos:notation	RIV/61389005:_____/09:00320910!RIV09-AV0-61389005
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA202/05/2728), P(GD202/05/H031), Z(AV0Z10100502), Z(AV0Z10480505)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Palajová, Zdenka Štěpán, Václav Davídková, Marie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav jaderné fyziky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	323638
http://linked.open...ai/riv/idVysledku	RIV/61389005:_____/09:00320910
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	radiation biology; linear energy transfer; protons; Monte Carlo modeling (en)
http://linked.open.../riv/klicoveSlovo	protons radiation biology linear energy transfer Monte Carlo modeling
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[2F7A4E8FF265]
http://linked.open...i/riv/nazevZdroje	Applied Radiation and Isotopes
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Application of ionizing radiation in dosimetry and radiological physics Modelling of radiobiological mechanism of protons and light ions in cells and tissues
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	67
http://linked.open...iv/tvurceVysledku	Judas, Libor Štěpán, Václav Davídková, Marie Kundrát, Pavel Palajová, Zdenka
http://linked.open...ain/vavai/riv/wos	000263936500018
http://linked.open...n/vavai/riv/zamer	Jevy fyziky elementárních částic přesahující standardní model Jaderná fyzika a příbuzné obory v základním, aplikovaném a interdisciplinárním výzkumu
issn	0969-8043
number of pages	6 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage Lethal events in V79 cells irradiated by low-energy protons and correlations with distribution patterns of energy deposition, radical concentration and DNA damage

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