About: Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Byl připraven a charakterizován nový injikovatelný polymerní systém pro lokální chemoradioterapii s vázaným radionuklidem a doxorubicinem jako skupinou, která kromě svého protinádorového působení funguje jako hydrofóbní jednotka řídící biodegradaci. Doxorubicin byl na polymer navázán nově vyvinutou N-glykosylaminovou vazbou. (cs) A new polymeric drug delivery system designed for possible local chemoradiotherapy using injectable thermoresponsive polymer with radionuclide and doxorubicin, which serves as an antiproliferative agent and hydrophobic moiety controlling bioerosion in the same time, was synthesized and characterized. Doxorubicin is bound to the polymer carrier by a newly developed N-glycosylamine bond. A new polymeric drug delivery system designed for possible local chemoradiotherapy using injectable thermoresponsive polymer with radionuclide and doxorubicin, which serves as an antiproliferative agent and hydrophobic moiety controlling bioerosion in the same time, was synthesized and characterized. Doxorubicin is bound to the polymer carrier by a newly developed N-glycosylamine bond. (en)
Title	Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond (en) Termoresponsivní polymery pro lokální radioterapii s doxorubicinem vázaným nově vyvinutou hydrolyticky labilní vazbou (cs)
skos:prefLabel	Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond (en) Termoresponsivní polymery pro lokální radioterapii s doxorubicinem vázaným nově vyvinutou hydrolyticky labilní vazbou (cs)
skos:notation	RIV/61389005:_____/08:00306669!RIV08-AV0-61389005
http://linked.open.../vavai/riv/strany	174;177
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IAA400480616), P(KAN200200651), Z(AV0Z10480505), Z(AV0Z40500505)
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Kučka, Jan Lebeda, Ondřej
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav jaderné fyziky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	399948
http://linked.open...ai/riv/idVysledku	RIV/61389005:_____/08:00306669
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	thermoresponsive; local; radiotherapy (en)
http://linked.open.../riv/klicoveSlovo	radiotherapy local thermoresponsive
http://linked.open...ontrolniKodProRIV	[DA5F4CFD189A]
http://linked.open...v/mistoKonaniAkce	Noordwijk aan Zee
http://linked.open...i/riv/mistoVydani	Noordwijk aan Zee
http://linked.open...i/riv/nazevZdroje	Abstract Book - Tenth European Symposium on Controlled Drug Delivery
http://linked.open...in/vavai/riv/obor	CD
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Nanoparticulate and supramolecular systems for targeted drug delivery Thermoresponsive polymeric drug delivery systems for local radiotherapy
http://linked.open...UplatneniVysledku	2008
http://linked.open...iv/tvurceVysledku	Hrubý, Martin Ulbrich, Karel Kučka, Jan Lebeda, Ondřej Koňák, Čestmír Větřík, M.
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2008-04-02 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Jaderná fyzika a příbuzné obory v základním, aplikovaném a interdisciplinárním výzkumu Progresivní makromolekulární materiály a supramolekulární systémy: syntéza a studium vlastností, jevů a možností využití pro speciální aplikace a moderní technologie
number of pages	4 (xsd:int)
http://purl.org/ne...btex#hasPublisher	University of Twente
https://schema.org/isbn	978-90-365-2653-1
is http://linked.open...avai/riv/vysledek of	Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond

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