About: Hepatic vascular isolation and perfusion for patients with progressive unresectable liver metastases from colorectal carcinoma refractory to previous systemic and regional chemotherapy.

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About: Hepatic vascular isolation and perfusion for patients with progressive unresectable liver metastases from colorectal carcinoma refractory to previous systemic and regional chemotherapy. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	BACKGROUND. Many patients with colorectal carcinoma develop unresectable metastases confined to the liver that remain the life-limiting component of disease despite best available systemic or regional chemotherapy. In the current study, the authors present their results using vascular isolation and perfusion of the liver for individuals with progressive, unresectable liver metastases from colorectal carcinoma that were refractory to both previous systemic and regional chemotherapy. METHODS. Seven patients with refractory, progressive, unresectable colorectal. carcinoma metastases confined to the liver underwent a 60-minute hyperthermic (39-40 degreesC) isolated hepatic perfusion (IHP) and were followed for toxicity, response, and survival. RESULTS, There was no surgical- or treatment- related mortality; all patients experienced transient Grade 3-4 (according to National Cancer Institute common toxicity criteria) hepatic toxicity. At a median potential follow-up of 16 months, the overall objective radi BACKGROUND. Many patients with colorectal carcinoma develop unresectable metastases confined to the liver that remain the life-limiting component of disease despite best available systemic or regional chemotherapy. In the current study, the authors present their results using vascular isolation and perfusion of the liver for individuals with progressive, unresectable liver metastases from colorectal carcinoma that were refractory to both previous systemic and regional chemotherapy. METHODS. Seven patients with refractory, progressive, unresectable colorectal. carcinoma metastases confined to the liver underwent a 60-minute hyperthermic (39-40 degreesC) isolated hepatic perfusion (IHP) and were followed for toxicity, response, and survival. RESULTS, There was no surgical- or treatment- related mortality; all patients experienced transient Grade 3-4 (according to National Cancer Institute common toxicity criteria) hepatic toxicity. At a median potential follow-up of 16 months, the overall objective radi (en)
Title	Hepatic vascular isolation and perfusion for patients with progressive unresectable liver metastases from colorectal carcinoma refractory to previous systemic and regional chemotherapy. Hepatic vascular isolation and perfusion for patients with progressive unresectable liver metastases from colorectal carcinoma refractory to previous systemic and regional chemotherapy. (en)
skos:prefLabel	Hepatic vascular isolation and perfusion for patients with progressive unresectable liver metastases from colorectal carcinoma refractory to previous systemic and regional chemotherapy. Hepatic vascular isolation and perfusion for patients with progressive unresectable liver metastases from colorectal carcinoma refractory to previous systemic and regional chemotherapy. (en)
skos:notation	RIV/61389005:_____/02:49033167!RIV/2004/AV0/A49004/N
http://linked.open.../vavai/riv/strany	730;736
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(KSK4055109)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Kranda, Karel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav jaderné fyziky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	647504
http://linked.open...ai/riv/idVysledku	RIV/61389005:_____/02:49033167
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	colorectal carcinoma; liver metastases; regional chemotherapy (en)
http://linked.open.../riv/klicoveSlovo	liver metastases colorectal carcinoma regional chemotherapy
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[2F460A275F9B]
http://linked.open...i/riv/nazevZdroje	CANCER
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Physics, chemistry and informatics for biological, ecological and medicinal applications
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	95
http://linked.open...iv/tvurceVysledku	Kranda, Karel Alexander, H. R. Libutti, S. K. Barlett, D. L. Beresnev, T. Helsabeck, C. Pingpank, J. F.
issn	0008-543X
number of pages	7 (xsd:int)

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