About: Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Microsomal fraction of fungal cells grabs the attention of many researchers for it contains enzymes that play a role in biotechnologically relevant processes. Microsomal enzymes, namely, CYP450s, were shown to metabolize a wide range of xenobiotic compounds, including PAHs, PCBs, dioxins, and endocrine disruptors, and take part in other fungal biotransformation reactions. However, little is known about the nature and regulation of these membrane-associated reactions. Advanced proteomic and post-genomic techniques make it possible to identify larger numbers of microsomal proteins and thus add to a deeper study of fungal intracellular processes. In this work, proteins that were identified through a shotgun proteomic approach in fungal microsomes under various culture conditions are reviewed. However, further research is still needed to fully understand the role of microsomes in fungal biodegradation and biotransformation reactions Microsomal fraction of fungal cells grabs the attention of many researchers for it contains enzymes that play a role in biotechnologically relevant processes. Microsomal enzymes, namely, CYP450s, were shown to metabolize a wide range of xenobiotic compounds, including PAHs, PCBs, dioxins, and endocrine disruptors, and take part in other fungal biotransformation reactions. However, little is known about the nature and regulation of these membrane-associated reactions. Advanced proteomic and post-genomic techniques make it possible to identify larger numbers of microsomal proteins and thus add to a deeper study of fungal intracellular processes. In this work, proteins that were identified through a shotgun proteomic approach in fungal microsomes under various culture conditions are reviewed. However, further research is still needed to fully understand the role of microsomes in fungal biodegradation and biotransformation reactions (en)
Title	Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions (en)
skos:prefLabel	Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions Fungal microsomes in a biotransformation perspective: protein nature of membrane-associated reactions (en)
skos:notation	RIV/61388971:_____/13:00422882!RIV14-TA0-61388971
http://linked.open...avai/predkladatel	Mikrobiologický ústav AV ČR, v.v.i.
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(TE01020218)
http://linked.open...iv/cisloPeriodika	24
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Petráčková, Denisa Svobodová, Kateřina Mikesková, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	75911
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/13:00422882
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Fungal microsomes; Cytochrome P450; Biodegradation (en)
http://linked.open.../riv/klicoveSlovo	Cytochrome P450 Biodegradation Fungal microsomes
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[EEEFBADE6589]
http://linked.open...i/riv/nazevZdroje	Applied Microbiology and Biotechnology
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Environmental friendly nanotechnologies and biotechnologies in water and soil treatment
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	97
http://linked.open...iv/tvurceVysledku	Svobodová, Kateřina Mikesková, Hana Petráčková, Denisa
http://linked.open...ain/vavai/riv/wos	000327495000003
issn	0175-7598
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s00253-013-5347-2

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