About: Lucifensin II, a Defensin of Medicinal Maggots of the Blowfly Lucilia cuprina (Diptera: Calliphoridae)

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About: Lucifensin II, a Defensin of Medicinal Maggots of the Blowfly Lucilia cuprina (Diptera: Calliphoridae) Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A novel homolog of insect defensin, designated lucifensin II (Lucilia cuprina Wiedemann [Diptera: Calliphoridae] defensin), was purified from hemolymph extract from larvae of the blowfly L. cuprina. The full-length primary sequence of this peptide of 40 amino acid residues and three intramolecular disulfide bridges was determined by electrospray ionization-orbitrap mass spectrometry and Edman degradation and is almost identical to the previously identified sequence of lucifensin (Lucilia sericata Meigen defensin). Lucifensin II sequence differs from that of lucifensin by only one amino acid residue, that is, by isoleucine instead of valine at position 11. The presence of lucifensin II also was detected in the extracts of other larval tissues, such as gut, salivary glands, fat body, and whole body extract. A novel homolog of insect defensin, designated lucifensin II (Lucilia cuprina Wiedemann [Diptera: Calliphoridae] defensin), was purified from hemolymph extract from larvae of the blowfly L. cuprina. The full-length primary sequence of this peptide of 40 amino acid residues and three intramolecular disulfide bridges was determined by electrospray ionization-orbitrap mass spectrometry and Edman degradation and is almost identical to the previously identified sequence of lucifensin (Lucilia sericata Meigen defensin). Lucifensin II sequence differs from that of lucifensin by only one amino acid residue, that is, by isoleucine instead of valine at position 11. The presence of lucifensin II also was detected in the extracts of other larval tissues, such as gut, salivary glands, fat body, and whole body extract. (en)
Title	Lucifensin II, a Defensin of Medicinal Maggots of the Blowfly Lucilia cuprina (Diptera: Calliphoridae) Lucifensin II, a Defensin of Medicinal Maggots of the Blowfly Lucilia cuprina (Diptera: Calliphoridae) (en)
skos:prefLabel	Lucifensin II, a Defensin of Medicinal Maggots of the Blowfly Lucilia cuprina (Diptera: Calliphoridae) Lucifensin II, a Defensin of Medicinal Maggots of the Blowfly Lucilia cuprina (Diptera: Calliphoridae) (en)
skos:notation	RIV/61388963:_____/13:00394138!RIV14-AV0-61388963
http://linked.open...avai/predkladatel	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Žďárek, Jan Fučík, Vladimír Čeřovský, Václav Veverka, Václav Voburka, Zdeněk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	85550
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/13:00394138
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Lucilia cuprina; insect defensin; lucifensin; sequence determination; maggot therapy (en)
http://linked.open.../riv/klicoveSlovo	Lucilia cuprina insect defensin maggot therapy sequence determination lucifensin
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[6E4589C0A644]
http://linked.open...i/riv/nazevZdroje	Journal of Medical Entomology
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	50
http://linked.open...iv/tvurceVysledku	Fučík, Vladimír Čeřovský, Václav Žďárek, Jan Veverka, Václav Voburka, Zdeněk El Shazely, B.
http://linked.open...ain/vavai/riv/wos	000319123600012
issn	0022-2585
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1603/ME12208

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