About: Ecdysteroid glycosides: Identification, Chromatographic properties, and biological significance

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Ecdysteroid glycosides are found in both animals and plants. The chromatographic behavior of these molecules is characteristic, as they appear much more polar than their corresponding free aglycones, whereas the presence of glycosidic moieties has a very limited (if any) impact on polarity when using reversed-phase HPLC. Biological activity is greatly reduced because the presence of this bulky substituent probably impairs the interaction with ecdysteroid receptors. Ecdysteroid glycosides are found in both animals and plants. The chromatographic behavior of these molecules is characteristic, as they appear much more polar than their corresponding free aglycones, whereas the presence of glycosidic moieties has a very limited (if any) impact on polarity when using reversed-phase HPLC. Biological activity is greatly reduced because the presence of this bulky substituent probably impairs the interaction with ecdysteroid receptors. (en) Glykosidy ekdysteroidů se nachází jak v živočiších tak i v rostlinách. Mají charakteristické chromatografické vlastnosti. Jsou omnoho polárnější než jejich aglykony v NP-HPLC, ovšem v RP-HPLC glykosylová skupina nemá téměř žádny vliv na polaritu. Jejich biologické aktivity jsou převážně slabší, pravděpodobně proto, že přítomnost objemné glykosylové skupiny brání interakci s ekdysteroidním receptorem. (cs)
Title	Ecdysteroid glycosides: Identification, Chromatographic properties, and biological significance Ecdysteroid glycosides: Identification, Chromatographic properties, and biological significance (en) Glykosidy ekdysteroidů: Identifikace, chromatografické vlastnosti a biologický význam (cs)
skos:prefLabel	Ecdysteroid glycosides: Identification, Chromatographic properties, and biological significance Ecdysteroid glycosides: Identification, Chromatographic properties, and biological significance (en) Glykosidy ekdysteroidů: Identifikace, chromatografické vlastnosti a biologický význam (cs)
skos:notation	RIV/61388963:_____/05:00021060!RIV06-AV0-61388963
http://linked.open.../vavai/riv/strany	149;157
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Harmatha, Juraj
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	519059
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/05:00021060
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ecdysteroid glycosides; HPLC; biological activity (en)
http://linked.open.../riv/klicoveSlovo	ecdysteroid glycosides HPLC biological activity
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[C16B5E78FABE]
http://linked.open...i/riv/nazevZdroje	Journal of Chromatographic Science
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	43
http://linked.open...iv/tvurceVysledku	Harmatha, Juraj Dinan, L. Lafont, R. Saatov, Z. Girault, J. P. Maria, A.
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	0021-9665
number of pages	9 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Ecdysteroid glycosides: Identification, Chromatographic properties, and biological significance

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