About: Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity

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About: Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this paper we examine influenced of N-glycosylation of glutamate carboxypeptidase II (GCPII, E.C.xxxx) on its hydrolytic activity. N-glycosylation was shown to be indispensable for GCPII carboxypeptidase activity and, additionally, site-directed mutagenesis of the individual N-glycosylation sequons identified contribution of each N-glycosylation site to this phenomenon In this paper we examine influenced of N-glycosylation of glutamate carboxypeptidase II (GCPII, E.C.xxxx) on its hydrolytic activity. N-glycosylation was shown to be indispensable for GCPII carboxypeptidase activity and, additionally, site-directed mutagenesis of the individual N-glycosylation sequons identified contribution of each N-glycosylation site to this phenomenon (en) V této publikaci jsme prozkoumali vliv N-glykosylačních míst na glutamátkarboxypeptidase II (GCPII) pro její proteolytickou aktivitu. N-glykosylace se ukázala být nezbytná pro karboxypeptidasovou aktivitu, navíc jsme pomocí bodové mutagenese jednotlivých N-glykosylačních míst identifikovali jejich příspěvek k tomuto fenoménu (cs)
Title	Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity (en) Identifikace N-glykosylačních míst na glutamátkarboxypeptidase II nezbytných pro proteolytickou aktivitu (cs)
skos:prefLabel	Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity (en) Identifikace N-glykosylačních míst na glutamátkarboxypeptidase II nezbytných pro proteolytickou aktivitu (cs)
skos:notation	RIV/61388963:_____/04:00101973!RIV/2005/GA0/A57005/N
http://linked.open.../vavai/riv/strany	1627;1635
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA301/03/0784), P(IAA5055108), Z(AV0Z4055905), Z(MSM 113100001)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Šácha, Pavel Konvalinka, Jan Bařinka, Cyril
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	567189
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/04:00101973
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	glycosylation; proteolytic activity; enzyme kinetics (en)
http://linked.open.../riv/klicoveSlovo	enzyme kinetics proteolytic activity glycosylation
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[5EE5E834DDB7]
http://linked.open...i/riv/nazevZdroje	Protein Science
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Membrane-bound carboxypeptidases: stricture, activity and their role in prostate cancer and neurotoxicity Molecular characterisation of glutamate carboxylace II, a neuropeptidase from human brain
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	13
http://linked.open...iv/tvurceVysledku	Bezouška, Karel Konvalinka, Jan Man, Petr Sklenář, Jan Šácha, Pavel Bařinka, Cyril Slusher, B. S.
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20113100001 Chemical principles of selected biological phenomena in medicine and ecology
issn	0961-8368
number of pages	9 (xsd:int)

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