Synthesis of homochiral .alfa.-amino acids 3a-3e and bis(.alfa.-amino acid)s 4a-4e via BF 3 .Et 2 O-catalyzed ring-opening of methyl ( S )-1-[(benzyloxy)carbonyl]aziridine-2-carboxylate (7) with oligo(ethylene glycol)s and subsequent acid hydrolysis is reported.
Synthesis of homochiral .alfa.-amino acids 3a-3e and bis(.alfa.-amino acid)s 4a-4e via BF 3 .Et 2 O-catalyzed ring-opening of methyl ( S )-1-[(benzyloxy)carbonyl]aziridine-2-carboxylate (7) with oligo(ethylene glycol)s and subsequent acid hydrolysis is reported. (en)