About: Magnesium and biological activity of oxytocin analogues modified on aromatic ring of amino acid in position 2.

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About: Magnesium and biological activity of oxytocin analogues modified on aromatic ring of amino acid in position 2. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	6 OT analogues ([D- and L- m -Me-Phe 2 ]OT, [D-and L- m -OMe-Phe 2 ]OT and [D- and L- o -Me-Tyr 2 ]OT) were synthesized and several previously described analogues resynthesized. Is was found that in the absence of Mg2+ substitution of the o - and m -position leads to loss of intrinsic activity in contrast to the p -position. 6 OT analogues ([D- and L- m -Me-Phe 2 ]OT, [D-and L- m -OMe-Phe 2 ]OT and [D- and L- o -Me-Tyr 2 ]OT) were synthesized and several previously described analogues resynthesized. Is was found that in the absence of Mg2+ substitution of the o - and m -position leads to loss of intrinsic activity in contrast to the p -position. (en)
Title	Magnesium and biological activity of oxytocin analogues modified on aromatic ring of amino acid in position 2. Magnesium and biological activity of oxytocin analogues modified on aromatic ring of amino acid in position 2. (en)
skos:prefLabel	Magnesium and biological activity of oxytocin analogues modified on aromatic ring of amino acid in position 2. Magnesium and biological activity of oxytocin analogues modified on aromatic ring of amino acid in position 2. (en)
skos:notation	RIV/61388963:_____/01:57010169!RIV/2003/AV0/A57003/N
http://linked.open.../vavai/riv/strany	413;424
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA204/99/1453), P(IAA4055602), P(LN00A032), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	N/A
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Slaninová, Jiřina Vondrášek, Jiří Maletínská, Lenka Procházka, Zdenko
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	685682
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/01:57010169
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	magnesium; - oxytocin analogues (en)
http://linked.open.../riv/klicoveSlovo	- oxytocin analogues magnesium
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[9D952B4C3D16]
http://linked.open...i/riv/nazevZdroje	Journal of Peptide Science
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Structure and dynamics of complex molecular systems and biomolecules Magnesium and oxytocin action Antagonism of the uterotonic oxytocic activity and position of the substitution in the arom. ring of the amino acid in position 2 of oxytocin and VP.
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	7
http://linked.open...iv/tvurceVysledku	Maletínská, Lenka Slaninová, Jiřina Vondrášek, Jiří Procházka, Zdenko
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	1075-2617
number of pages	12 (xsd:int)

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