About: SIFT-MS Analysis of Nose-Exhaled Breath; Mouth Contamination and the Influence of Exercise     Goto   Sponge   NotDistinct   Permalink

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  • The value of selected ion flow tube mass spectrometry, SIFT-MS, for the sampling and analysis of trace me- tabolites in both mouth-exhaled and nose-exhaled breath is discussed, and the latter is shown to circumvent oral contami- nation. Results of experiments are described in which increased levels of ammonia and ethanol deliberately generated in the oral cavity are clearly registered in mouth-exhaled breath but not in nose-exhaled breath. The value of the sampling methods that are used for the analysis of trace metabolites in both mouth-exhaled and nose-exhaled breath with selected ion flow tube mass spectrometry, SIFT-MS, is discussed, and their importance as a means to provide concentrations of truly endogenous compounds by circumventing their oral contamination is demonstrated. Further to this, data are pre- sented on the direct analysis by SIFT-MS of several compounds in the nose-exhaled breath of eight healthy volunteers during exercise on a stationary bicycle. Of note are the data on breath isoprene, which is seen to increase during exercise above the respective resting levels for all eight volunteers by a factor of 2 or 3 times, this being in accordance with previ- ous observations. Taken together, the results of this study show the value and simplicity of direct analysis of nose-exhaled breath by SIFT-MS, which can provide immediate results to the clinician and sports physiologists with no pain or discom- fort to the volunteer or patient.
  • The value of selected ion flow tube mass spectrometry, SIFT-MS, for the sampling and analysis of trace me- tabolites in both mouth-exhaled and nose-exhaled breath is discussed, and the latter is shown to circumvent oral contami- nation. Results of experiments are described in which increased levels of ammonia and ethanol deliberately generated in the oral cavity are clearly registered in mouth-exhaled breath but not in nose-exhaled breath. The value of the sampling methods that are used for the analysis of trace metabolites in both mouth-exhaled and nose-exhaled breath with selected ion flow tube mass spectrometry, SIFT-MS, is discussed, and their importance as a means to provide concentrations of truly endogenous compounds by circumventing their oral contamination is demonstrated. Further to this, data are pre- sented on the direct analysis by SIFT-MS of several compounds in the nose-exhaled breath of eight healthy volunteers during exercise on a stationary bicycle. Of note are the data on breath isoprene, which is seen to increase during exercise above the respective resting levels for all eight volunteers by a factor of 2 or 3 times, this being in accordance with previ- ous observations. Taken together, the results of this study show the value and simplicity of direct analysis of nose-exhaled breath by SIFT-MS, which can provide immediate results to the clinician and sports physiologists with no pain or discom- fort to the volunteer or patient. (en)
Title
  • SIFT-MS Analysis of Nose-Exhaled Breath; Mouth Contamination and the Influence of Exercise
  • SIFT-MS Analysis of Nose-Exhaled Breath; Mouth Contamination and the Influence of Exercise (en)
skos:prefLabel
  • SIFT-MS Analysis of Nose-Exhaled Breath; Mouth Contamination and the Influence of Exercise
  • SIFT-MS Analysis of Nose-Exhaled Breath; Mouth Contamination and the Influence of Exercise (en)
skos:notation
  • RIV/61388955:_____/13:00421269!RIV14-AV0-61388955
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 2013
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 105018
http://linked.open...ai/riv/idVysledku
  • RIV/61388955:_____/13:00421269
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • selected ion flow tube mass spectrometry; breath analysis; nose exhalation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [183E28C6BDD4]
http://linked.open...i/riv/nazevZdroje
  • Current Analytical Chemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 9
http://linked.open...iv/tvurceVysledku
  • Chippendale, T. W. E.
  • Dryahina, Kseniya
  • Smith, D.
  • Španěl, Patrik
http://linked.open...ain/vavai/riv/wos
  • 000324493100006
issn
  • 1573-4110
number of pages
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