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Description
| - The value of selected ion flow tube mass spectrometry, SIFT-MS, for the sampling and analysis of trace me- tabolites in both mouth-exhaled and nose-exhaled breath is discussed, and the latter is shown to circumvent oral contami- nation. Results of experiments are described in which increased levels of ammonia and ethanol deliberately generated in the oral cavity are clearly registered in mouth-exhaled breath but not in nose-exhaled breath. The value of the sampling methods that are used for the analysis of trace metabolites in both mouth-exhaled and nose-exhaled breath with selected ion flow tube mass spectrometry, SIFT-MS, is discussed, and their importance as a means to provide concentrations of truly endogenous compounds by circumventing their oral contamination is demonstrated. Further to this, data are pre- sented on the direct analysis by SIFT-MS of several compounds in the nose-exhaled breath of eight healthy volunteers during exercise on a stationary bicycle. Of note are the data on breath isoprene, which is seen to increase during exercise above the respective resting levels for all eight volunteers by a factor of 2 or 3 times, this being in accordance with previ- ous observations. Taken together, the results of this study show the value and simplicity of direct analysis of nose-exhaled breath by SIFT-MS, which can provide immediate results to the clinician and sports physiologists with no pain or discom- fort to the volunteer or patient.
- The value of selected ion flow tube mass spectrometry, SIFT-MS, for the sampling and analysis of trace me- tabolites in both mouth-exhaled and nose-exhaled breath is discussed, and the latter is shown to circumvent oral contami- nation. Results of experiments are described in which increased levels of ammonia and ethanol deliberately generated in the oral cavity are clearly registered in mouth-exhaled breath but not in nose-exhaled breath. The value of the sampling methods that are used for the analysis of trace metabolites in both mouth-exhaled and nose-exhaled breath with selected ion flow tube mass spectrometry, SIFT-MS, is discussed, and their importance as a means to provide concentrations of truly endogenous compounds by circumventing their oral contamination is demonstrated. Further to this, data are pre- sented on the direct analysis by SIFT-MS of several compounds in the nose-exhaled breath of eight healthy volunteers during exercise on a stationary bicycle. Of note are the data on breath isoprene, which is seen to increase during exercise above the respective resting levels for all eight volunteers by a factor of 2 or 3 times, this being in accordance with previ- ous observations. Taken together, the results of this study show the value and simplicity of direct analysis of nose-exhaled breath by SIFT-MS, which can provide immediate results to the clinician and sports physiologists with no pain or discom- fort to the volunteer or patient. (en)
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Title
| - SIFT-MS Analysis of Nose-Exhaled Breath; Mouth Contamination and the Influence of Exercise
- SIFT-MS Analysis of Nose-Exhaled Breath; Mouth Contamination and the Influence of Exercise (en)
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skos:prefLabel
| - SIFT-MS Analysis of Nose-Exhaled Breath; Mouth Contamination and the Influence of Exercise
- SIFT-MS Analysis of Nose-Exhaled Breath; Mouth Contamination and the Influence of Exercise (en)
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skos:notation
| - RIV/61388955:_____/13:00421269!RIV14-AV0-61388955
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http://linked.open...avai/predkladatel
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61388955:_____/13:00421269
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - selected ion flow tube mass spectrometry; breath analysis; nose exhalation (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Current Analytical Chemistry
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Chippendale, T. W. E.
- Dryahina, Kseniya
- Smith, D.
- Španěl, Patrik
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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