About: Oxidation of sterols: Energetics of C–H and O

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Oxidation of sterols: Energetics of C–H and O–H bond cleavage Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Phytosterols, as components of human diet, received much attention because of their cholesterol-lowering and antioxidant properties. We have theoretically studied sterols oxidation in terms of O–H and C–H bond dissociation enthalpies (BDE). In 17 Δ5- and Δ7-sterols, BDEs were obtained for reported sites of oxidation attack. Obtained results indicate that Δ7-sterols are more susceptible to oxidation attack in comparison to Δ5-sterols. In sterol nuclei, the lowest BDE was found for C7–H bond in Δ5-sterols and for C14–H in Δ7-sterols. When Δ5-sterol has a C=C double bond in the side chain, the lowest BDEs are usually found for C–H bonds in α-positions to this bond. The homolytic cleavage of hydroxyl O–H bond requires larger energy in comparison to the studied C–H bonds. We have shown that the C–H bonds with lowest BDE values actually correspond to the dominant sites of oxidation attack. Phytosterols, as components of human diet, received much attention because of their cholesterol-lowering and antioxidant properties. We have theoretically studied sterols oxidation in terms of O–H and C–H bond dissociation enthalpies (BDE). In 17 Δ5- and Δ7-sterols, BDEs were obtained for reported sites of oxidation attack. Obtained results indicate that Δ7-sterols are more susceptible to oxidation attack in comparison to Δ5-sterols. In sterol nuclei, the lowest BDE was found for C7–H bond in Δ5-sterols and for C14–H in Δ7-sterols. When Δ5-sterol has a C=C double bond in the side chain, the lowest BDEs are usually found for C–H bonds in α-positions to this bond. The homolytic cleavage of hydroxyl O–H bond requires larger energy in comparison to the studied C–H bonds. We have shown that the C–H bonds with lowest BDE values actually correspond to the dominant sites of oxidation attack. (en)
Title	Oxidation of sterols: Energetics of C–H and O–H bond cleavage Oxidation of sterols: Energetics of C–H and O–H bond cleavage (en)
skos:prefLabel	Oxidation of sterols: Energetics of C–H and O–H bond cleavage Oxidation of sterols: Energetics of C–H and O–H bond cleavage (en)
skos:notation	RIV/61388955:_____/12:00376443!RIV13-GA0-61388955
http://linked.open...avai/predkladatel	Ústav fyzikální chemie J. Heyrovského AV ČR, v.v.i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP208/11/0161), Z(AV0Z40400503)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Lengyel, Jozef
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav fyzikální chemie J. Heyrovského AV ČR, v.v.i.
http://linked.open...dnocenehoVysledku	157548
http://linked.open...ai/riv/idVysledku	RIV/61388955:_____/12:00376443
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	phytosterol; oxidation; antioxidant (en)
http://linked.open.../riv/klicoveSlovo	oxidation phytosterol antioxidant
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[CCBF38519BB4]
http://linked.open...i/riv/nazevZdroje	Food Chemistry
http://linked.open...in/vavai/riv/obor	CF
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Dynamicss of Solvated Electrons in Molecular Clusters: Experimental and Theoretical Approach
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	133
http://linked.open...iv/tvurceVysledku	Fedor, J. Lengyel, Jozef Klein, E. Lukeš, V. Rimarčík, J. Vagánek, A.
http://linked.open...ain/vavai/riv/wos	000303847400045
http://linked.open...n/vavai/riv/zamer	Struktura, reaktivita a dynamika molekulárních a biomolekulárních systémů: teorie, experiment, aplikace
issn	0308-8146
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.foodchem.2012.02.031
is http://linked.open...avai/riv/vysledek of	Oxidation of sterols: Energetics of C–H and O–H bond cleavage

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software