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| rdf:type
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| Description
| - Užívání relativně velkých dávek Niacinu zdravými dobrovolníky vede k zarudnutí pokožky, ´zčervenání´. Provedli jsme výzkum metabolitů v dechu zdravých dobrovolníků po (i) užití 200 mg niacinu s okamžitým uvolněním (ii) stejně jako (i) ale až po užití 325 mg aspirinu která umenšuji zčervenání (iii) užití 500 mg niacinu s pomalým uvolňováním. Analýza dechu byla provedena s použitím hmotnostní spektrometrie v proudové trubici s vybranými ionty. Hladina amoniaku v dechu byla zvýšena v případech (i) a (ii) ale ne v případě (iii). Zčervenání bylo pozorováno pouze v případě (i). Výsledky ukazují, že koncentrace čpavku je ovlivněna hladinou niacinu v krvi ale nesouvisí s fenoménem zčervenání. (cs)
- The ingestion of relatively large doses of the vitamin niacin by healthy volunteers results in a reddening of the skin, a skin 'flush'. Thus, we have carried out a study of the breath metabolites of two healthy volunteers following (i) the ingestion of 200 mg of immediate-release niacin, (ii) as (i) but preceded by the ingestion of 325 mg of aspirin that diminishes the skin 'flush', (iii) ingestion of 500 mg of slow-release niacin. On-line breath analysis was carried out using selected ion flow tube mass spectrometry, SIFT-MS. The interesting new observation is that the breath ammonia levels of both volunteers clearly increased following (i) and (ii), and an obvious skin flush did occur following (i) but not following (ii). The slow-release niacin (iii) did not result in a flush and the breath ammonia levels increased more slowly and did not reach the higher levels produced by (i) and (ii).
- The ingestion of relatively large doses of the vitamin niacin by healthy volunteers results in a reddening of the skin, a skin 'flush'. Thus, we have carried out a study of the breath metabolites of two healthy volunteers following (i) the ingestion of 200 mg of immediate-release niacin, (ii) as (i) but preceded by the ingestion of 325 mg of aspirin that diminishes the skin 'flush', (iii) ingestion of 500 mg of slow-release niacin. On-line breath analysis was carried out using selected ion flow tube mass spectrometry, SIFT-MS. The interesting new observation is that the breath ammonia levels of both volunteers clearly increased following (i) and (ii), and an obvious skin flush did occur following (i) but not following (ii). The slow-release niacin (iii) did not result in a flush and the breath ammonia levels increased more slowly and did not reach the higher levels produced by (i) and (ii). (en)
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| Title
| - The increase of breath ammonia induced by niacin ingestion quantified by selected ion flow tube mass spectrometry
- Zvýšený amoniak v dechu indukovaný užíváním niacinu měřený s použitím hmotnostní spektrometrie v proudové trubici s vybranými ionty (cs)
- The increase of breath ammonia induced by niacin ingestion quantified by selected ion flow tube mass spectrometry (en)
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| skos:prefLabel
| - The increase of breath ammonia induced by niacin ingestion quantified by selected ion flow tube mass spectrometry
- Zvýšený amoniak v dechu indukovaný užíváním niacinu měřený s použitím hmotnostní spektrometrie v proudové trubici s vybranými ionty (cs)
- The increase of breath ammonia induced by niacin ingestion quantified by selected ion flow tube mass spectrometry (en)
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| skos:notation
| - RIV/61388955:_____/06:00078422!RIV07-AV0-61388955
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/61388955:_____/06:00078422
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| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - SIFT-MS; ammonia; breath analysis; niacin (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Physiological Measurement
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Smith, D.
- Španěl, Patrik
- Wang, T. S.
- Bloor, R.
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| is http://linked.open...avai/riv/vysledek
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