About: Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation

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About: Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this study, a dynamic model is presented for the granulation process, employing a three-dimensional Population balance framework. As a first attempt to account for the multi-scale character of the process, the nucleation and aggregation kernels used in the population balance model are derived using mechanistic representations of the underlying particle physics such as wetting kinetics and energy dissipation effects. Thus, the fundamental properties of the powder and the liquid were used as parameters in the model to predict the granulator dynamics and granule properties. The population balance model is validated against experimental data from a calcite/PVOH-H2O recipe obtained using a lab-scale drum granulator for granule size, fractional binder content and porosity. A reasonably good agreement between experimental and simulation results were obtained for the granule size distribution under different experimental conditions. In addition, accurate model predictions were made for the evolution of the In this study, a dynamic model is presented for the granulation process, employing a three-dimensional Population balance framework. As a first attempt to account for the multi-scale character of the process, the nucleation and aggregation kernels used in the population balance model are derived using mechanistic representations of the underlying particle physics such as wetting kinetics and energy dissipation effects. Thus, the fundamental properties of the powder and the liquid were used as parameters in the model to predict the granulator dynamics and granule properties. The population balance model is validated against experimental data from a calcite/PVOH-H2O recipe obtained using a lab-scale drum granulator for granule size, fractional binder content and porosity. A reasonably good agreement between experimental and simulation results were obtained for the granule size distribution under different experimental conditions. In addition, accurate model predictions were made for the evolution of the (en)
Title	Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation (en)
skos:prefLabel	Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation (en)
skos:notation	RIV/60461373:22340/09:00021914!RIV10-MSM-22340___
http://linked.open...avai/riv/aktivita	S
http://linked.open...avai/riv/aktivity	S
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Štěpánek, František
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta chemicko-inženýrská
http://linked.open...dnocenehoVysledku	314281
http://linked.open...ai/riv/idVysledku	RIV/60461373:22340/09:00021914
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	granulation; population balance modelling; model validation (en)
http://linked.open.../riv/klicoveSlovo	model validation population balance modelling granulation
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[629D591BB84A]
http://linked.open...i/riv/nazevZdroje	Chemical Engineering Science
http://linked.open...in/vavai/riv/obor	CI
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	64
http://linked.open...iv/tvurceVysledku	Štěpánek, František Doyle, F. J. Immanuel, C. D. Litster, J. D. Ramachandran, R. Cameron, IT. Glaser, T. Poon, JHM. Sanders, CFW. Wang, FY.
http://linked.open...ain/vavai/riv/wos	000263773900015
issn	0009-2509
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	22340
is http://linked.open...avai/riv/vysledek of	Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation

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