| Attributes | Values |
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| rdf:type
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| Description
| - Jednoduché ve vodě rozpustné komplexy lanthanu a europia jsou účinné při detekci neutrálních cukrů stejně jako glykolipidů a fosfolipidů V roztocích s pH blízkým fyziologickému se fluorescenční komplexy lanthanu vážou na neutrální cukry s vazebnou konstantou srovnatelnou s arylboronovými kyselinami. (cs)
- Simple water-soluble lanthanum and europium complexes are effective at detecting neutral sugars as well as glycolipids and phospholipids. In solutions at physiologically relevant pH the fluorescent lanthanum complex binds neutral sugars with apparent binding constants comparable to those of arylboronic acids. interference from commonly occurring anions is minimal. The europium complex detects sialic acid-containing gangliosides at pH 7.0 over an asialoganglioside. This selectivity is attributed, in large part, to the cooperative complexation of the oligosaccharicle and sialic acid residues to the metal center, based on analogous prior studies. In MeOH, lysophosphatidic acid (LPA), a biomarker for several pathological conditions including ovarian cancer, is selectively detected by the europium complex. LPA is also detected via a fluorescence increase in human plasma samples. The 2-sn-OH moiety of LPA plays a key role in promoting binding to the metal center. Other molecules found in common brain gangli
- Simple water-soluble lanthanum and europium complexes are effective at detecting neutral sugars as well as glycolipids and phospholipids. In solutions at physiologically relevant pH the fluorescent lanthanum complex binds neutral sugars with apparent binding constants comparable to those of arylboronic acids. interference from commonly occurring anions is minimal. The europium complex detects sialic acid-containing gangliosides at pH 7.0 over an asialoganglioside. This selectivity is attributed, in large part, to the cooperative complexation of the oligosaccharicle and sialic acid residues to the metal center, based on analogous prior studies. In MeOH, lysophosphatidic acid (LPA), a biomarker for several pathological conditions including ovarian cancer, is selectively detected by the europium complex. LPA is also detected via a fluorescence increase in human plasma samples. The 2-sn-OH moiety of LPA plays a key role in promoting binding to the metal center. Other molecules found in common brain gangli (en)
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| Title
| - Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers
- Lanthanidové komplexy jako fluorescenční indikátory pro neutrální cukry a rakovinné biomarkery (cs)
- Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers (en)
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| skos:prefLabel
| - Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers
- Lanthanidové komplexy jako fluorescenční indikátory pro neutrální cukry a rakovinné biomarkery (cs)
- Lanthanide complexes as fluorescent indicators for neutral sugars and cancer biomarkers (en)
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| skos:notation
| - RIV/60461373:22340/06:00016747!RIV07-MSM-22340___
|
| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(GA203/06/1038), P(LC512), Z(MSM6046137307)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/60461373:22340/06:00016747
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - gangliosides; lysophosphaticlic acid; salophenes; saccharides (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Proceedings of the National Academy of Sciences of U.S.A
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Král, Vladimír
- Wang, W.
- Rusín, Oleksandr
- Escobedo, J.
- Strongin, R.
- Alptürk, O.
- Crowe, W.
- Fakayode, S.
- Pruet, J.
- Warner, I.
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| http://linked.open...n/vavai/riv/zamer
| |
| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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