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rdf:type
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Description
| - At present, the importance of complexes, when the radionuclide was transported to tumor via antibody labeled by a and b emitters, increasingly grows in the targeted therapy of cancers. We were dealing with the study of the human immunoglobulin G (IgG) and anti-CD 20 conjugations with the bicyclic anhydride of the diethylentriamino-N,N,N,N,N-pentaacetate acid (cDTPAA) and labeling of prepared conjugates by 90Y (carrier-free) and 177Lu radionuclides. The HPLC - SEC method, the ultrafiltation and the gel was used for separationof the antibody - DTPA conjugate and free DTPA. The characterization of the bifunctional chelaton bond to antibody was carried out by FTIR spectroscopy.
- At present, the importance of complexes, when the radionuclide was transported to tumor via antibody labeled by a and b emitters, increasingly grows in the targeted therapy of cancers. We were dealing with the study of the human immunoglobulin G (IgG) and anti-CD 20 conjugations with the bicyclic anhydride of the diethylentriamino-N,N,N,N,N-pentaacetate acid (cDTPAA) and labeling of prepared conjugates by 90Y (carrier-free) and 177Lu radionuclides. The HPLC - SEC method, the ultrafiltation and the gel was used for separationof the antibody - DTPA conjugate and free DTPA. The characterization of the bifunctional chelaton bond to antibody was carried out by FTIR spectroscopy. (en)
- At present, the importance of complexes, when the radionuclide was transported to tumor via antibody labeled by a and b emitters, increasingly grows in the targeted therapy of cancers. We were dealing with the study of the human immunoglobulin G (IgG) and anti-CD 20 conjugations with the bicyclic anhydride of the diethylentriamino-N,N,N,N,N-pentaacetate acid (cDTPAA) and labeling of prepared conjugates by 90Y (carrier-free) and 177Lu radionuclides. The HPLC - SEC method, the ultrafiltation and the gel was used for separationof the antibody - DTPA conjugate and free DTPA. The characterization of the bifunctional chelaton bond to antibody was carried out by FTIR spectroscopy. (cs)
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Title
| - Metody pro charakterizaci konjugátů radionuklid - ligand - protilátka
- Metody pro charakterizaci konjugátů radionuklid - ligand - protilátka (en)
- Metody pro charakterizaci konjugátů radionuklid - ligand - protilátka (cs)
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skos:prefLabel
| - Metody pro charakterizaci konjugátů radionuklid - ligand - protilátka
- Metody pro charakterizaci konjugátů radionuklid - ligand - protilátka (en)
- Metody pro charakterizaci konjugátů radionuklid - ligand - protilátka (cs)
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skos:notation
| - RIV/60461373:22340/05:00014550!RIV06-GA0-22340___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA104/03/0499), Z(MSM6046137307)
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60461373:22340/05:00014550
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - radionuklid; ligand; protilátka (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Křížová, Věra
- Reková, Marie
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http://linked.open...n/vavai/riv/zamer
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http://localhost/t...ganizacniJednotka
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