About: The flow control in continuous chromatography

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	There is always a need to precisely distribute and control the flows in preparative chromatography, because it is the most important part of control in such kind of the process. In most cases the control is being made for one station as a black box with several inputs and outputs. We have made a small module, which can be connected up to the eight-columned station and corresponding number of pumps. It has its own controlling system consisting of controllers based on Siemens Simatic. It allows controlling any continuous process like SMB and VariCol. It consists of system of electromagnetic valves connected together with silicon tubes allowing distribution of flow in several directions. The functionality of distributor and primary control were tested with existing chromatographic unit KCHS-SMB-8-N containing sorbent Lewatit MDS 1368. The initial tests were performed with solutions of saccharides or carbohydrate and salts. The system for higher level control based on optimization and fuzzy logic is now being tested for the SMB mode. In a future, the VariCol system will be also tested using the food technology by-products like molasses and whey with aim to purify saccharides and proteins. There is always a need to precisely distribute and control the flows in preparative chromatography, because it is the most important part of control in such kind of the process. In most cases the control is being made for one station as a black box with several inputs and outputs. We have made a small module, which can be connected up to the eight-columned station and corresponding number of pumps. It has its own controlling system consisting of controllers based on Siemens Simatic. It allows controlling any continuous process like SMB and VariCol. It consists of system of electromagnetic valves connected together with silicon tubes allowing distribution of flow in several directions. The functionality of distributor and primary control were tested with existing chromatographic unit KCHS-SMB-8-N containing sorbent Lewatit MDS 1368. The initial tests were performed with solutions of saccharides or carbohydrate and salts. The system for higher level control based on optimization and fuzzy logic is now being tested for the SMB mode. In a future, the VariCol system will be also tested using the food technology by-products like molasses and whey with aim to purify saccharides and proteins. (en)
Title	The flow control in continuous chromatography The flow control in continuous chromatography (en)
skos:prefLabel	The flow control in continuous chromatography The flow control in continuous chromatography (en)
skos:notation	RIV/60461373:22330/14:43899302!RIV15-MSM-22330___
http://linked.open...avai/riv/aktivita	I
http://linked.open...avai/riv/aktivity	I
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Henke, Svatopluk Hinková, Andrea Pour, Vladimír Bubník, Zdeněk Hassan, Nazih
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta potravinářské a biochemické technologie
http://linked.open...dnocenehoVysledku	17050
http://linked.open...ai/riv/idVysledku	RIV/60461373:22330/14:43899302
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	SMB; flow; continuous chromatography (en)
http://linked.open.../riv/klicoveSlovo	SMB flow continuous chromatography
http://linked.open...ontrolniKodProRIV	[F1438F183F7D]
http://linked.open...v/mistoKonaniAkce	Praha
http://linked.open...i/riv/mistoVydani	Praha
http://linked.open...i/riv/nazevZdroje	Proceedings of the 21st International Congress of Chemical and Process Engineering CHISA 2014
http://linked.open...in/vavai/riv/obor	GM
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Bubník, Zdeněk Hassan, Nazih Henke, Svatopluk Hinková, Andrea Pour, Vladimír Vejs, L.
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2014-08-23 (xsd:date)
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Česká společnost chemického inženýrství
https://schema.org/isbn	978-80-02-02555-9
http://localhost/t...ganizacniJednotka	22330

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