About: Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Microbiological research is focused on solution of pathogen resistance problem. One of the potential solutions seems to be short cationic peptides naturally synthetized as a part of innate immunity. In our project larvae of the fleshly Neobellieria bullata were chosen as a source of these peptides. Several isolated fractions showed antimicrobial activity against bacteria and fungi. Tricine electrophoresis proved presence of low molecular peptide. MS analysis of antimicrobial active fractions determined molecular masses less than 10 kDa and the N-terminal sequencing gave us several sequences but not completed. The sequences do have very low similarity with peptides in the NCBI databases or with the database of antimicrobial peptides [2] and seem to be very unique Microbiological research is focused on solution of pathogen resistance problem. One of the potential solutions seems to be short cationic peptides naturally synthetized as a part of innate immunity. In our project larvae of the fleshly Neobellieria bullata were chosen as a source of these peptides. Several isolated fractions showed antimicrobial activity against bacteria and fungi. Tricine electrophoresis proved presence of low molecular peptide. MS analysis of antimicrobial active fractions determined molecular masses less than 10 kDa and the N-terminal sequencing gave us several sequences but not completed. The sequences do have very low similarity with peptides in the NCBI databases or with the database of antimicrobial peptides [2] and seem to be very unique (en)
Title	Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph (en)
skos:prefLabel	Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph (en)
skos:notation	RIV/60461373:22330/11:43892172!RIV12-MSM-22330___
http://linked.open...avai/predkladatel	Fakulta potravinářské a biochemické technologie
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA522/09/1693), P(GD305/09/H008), Z(MSM6046137305)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Neubauerová, Tereza Macková, Martina Macek, Tomáš
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta potravinářské a biochemické technologie
http://linked.open...dnocenehoVysledku	225285
http://linked.open...ai/riv/idVysledku	RIV/60461373:22330/11:43892172
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Neobellieria bullata; N-terminal sequencing; isolation; Antimicrobial peptides (en)
http://linked.open.../riv/klicoveSlovo	Antimicrobial peptides Neobellieria bullata isolation N-terminal sequencing
http://linked.open...ontrolniKodProRIV	[FCFD2E4EE307]
http://linked.open...i/riv/mistoVydani	Singapore
http://linked.open...vEdiceCisloSvazku	1
http://linked.open...i/riv/nazevZdroje	Science and Technology against Microbial Pathogens. Research, Development and Evaluation
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...v/pocetStranKnihy	432 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of antimicrobial peptides in plant defense against pahogenic microorganisms Preparation, biotransformation, and optimalization of compounds with antitumor and antimicrobial effects
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Macek, Tomáš Macková, Martina Neubauerová, Tereza Šanda, Miloslav Vobůrka, Zdeněk
http://linked.open...n/vavai/riv/zamer	Teoretické základy potravinářských a biochemických technologií
number of pages	5 (xsd:int)
http://purl.org/ne...btex#hasPublisher	World Scientific Publishing Co. Pte. Ltd.
https://schema.org/isbn	978-981-4354-85-1
http://localhost/t...ganizacniJednotka	22330
is http://linked.open...avai/riv/vysledek of	Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph

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