About: Cell interaction with modified titanium nanostructures

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Electrochemical oxidation of titanium allows preparing TiO2 tube layer with unique properties. This layer could be further modified to increase bioactivity. The aim of this work was to study the interaction of cells with various modified nanostructures on Ti6Al4V alloy. Nanotubes were prepared in a mixture of (NH4)2SO4 and NH4F.These surfaces were treated with calcium hydroxide solution, phosphoric acid and heat treated. Effect of each adjustment was controlled by SEM, XPS and Raman spectroscopy. To evaluate biological functionality of surface treatments cell line SaOS-2 was used. Cells activities were determined on day 1, 3 and 7 after seeding.Cell spreading area was evaluated on day 1 after seeding. However, cells on all tested samples displayed only slight reduce in comparison with polystyrene. The viability of the cells on all surfaces, evaluated by the LIVE/DEAD test, was higher than 90 % and there were no significant differences among the tested groups. The cell number was higher on both chemically treated nanostructures after 7 days of cultivation. Therefore, it can be concluded that chemically modified surfaces seem to be promising for biomaterials applications. Electrochemical oxidation of titanium allows preparing TiO2 tube layer with unique properties. This layer could be further modified to increase bioactivity. The aim of this work was to study the interaction of cells with various modified nanostructures on Ti6Al4V alloy. Nanotubes were prepared in a mixture of (NH4)2SO4 and NH4F.These surfaces were treated with calcium hydroxide solution, phosphoric acid and heat treated. Effect of each adjustment was controlled by SEM, XPS and Raman spectroscopy. To evaluate biological functionality of surface treatments cell line SaOS-2 was used. Cells activities were determined on day 1, 3 and 7 after seeding.Cell spreading area was evaluated on day 1 after seeding. However, cells on all tested samples displayed only slight reduce in comparison with polystyrene. The viability of the cells on all surfaces, evaluated by the LIVE/DEAD test, was higher than 90 % and there were no significant differences among the tested groups. The cell number was higher on both chemically treated nanostructures after 7 days of cultivation. Therefore, it can be concluded that chemically modified surfaces seem to be promising for biomaterials applications. (en)
Title	Cell interaction with modified titanium nanostructures Cell interaction with modified titanium nanostructures (en)
skos:prefLabel	Cell interaction with modified titanium nanostructures Cell interaction with modified titanium nanostructures (en)
skos:notation	RIV/60461373:22310/14:43898382!RIV15-MSM-22310___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(TE01020390), S
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Fojt, Jaroslav Joska, Luděk Moravec, Hynek
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoká škola chemicko-technologická v Praze / Fakulta chemické technologie
http://linked.open...dnocenehoVysledku	6395
http://linked.open...ai/riv/idVysledku	RIV/60461373:22310/14:43898382
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	titanium alloy, nanostructure, treatment, cell (en)
http://linked.open.../riv/klicoveSlovo	cell titanium alloy treatment nanostructure
http://linked.open...ontrolniKodProRIV	[6EBD686AA63D]
http://linked.open...v/mistoKonaniAkce	Brno
http://linked.open...i/riv/mistoVydani	Ostrava
http://linked.open...i/riv/nazevZdroje	Conference Proceedings 6th International Conference
http://linked.open...in/vavai/riv/obor	JK
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre of the development of advanced metallic biomaterials for medical implants
http://linked.open...UplatneniVysledku	2014
http://linked.open...iv/tvurceVysledku	Fojt, Jaroslav Joska, Luděk Vandrovcová, Marta Moravec, Hynek Chotová, Kateřina
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2014-11-05 (xsd:date)
number of pages	6 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Tanger s.r.o.
https://schema.org/isbn	978-80-87294-55-0
http://localhost/t...ganizacniJednotka	22310

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