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  • Platinum complexes are commonly used as homogeneous catalysts or as precursors of supported metal catalysts and a very important group of platinum complexes are also used as precursors to fine chemicals. Potassium aminetrichloridoplatinate(II), KPt[(NH3)Cl3], is one such compound and it is a valuable precursor to many biologically active platinum complexes that are used as drugs with cytostatic activity, e.g. Picoplatin, LA-12 and Cycloplatam K[Pt(NH3)Cl3] is mainly prepared from cis-diamminedichloridoplatinate(II), cis Pt(NH3)2Cl2 that has itself been used as an anticancer drug, cisplatin, since 1978. The disadvantages of such a synthesis of K[Pt(NH3)Cl3] are the aforementioned biological activity of cis Pt(NH3)2Cl2 and very low yields of the key product. Alternative syntheses start from the less biologically active potassium tetrachloridoplatinate(II), K2PtCl4, but yields are lower than for the processes starting from cisplatin. The aim of this work was to find a new synthetic route for the pre
  • Platinum complexes are commonly used as homogeneous catalysts or as precursors of supported metal catalysts and a very important group of platinum complexes are also used as precursors to fine chemicals. Potassium aminetrichloridoplatinate(II), KPt[(NH3)Cl3], is one such compound and it is a valuable precursor to many biologically active platinum complexes that are used as drugs with cytostatic activity, e.g. Picoplatin, LA-12 and Cycloplatam K[Pt(NH3)Cl3] is mainly prepared from cis-diamminedichloridoplatinate(II), cis Pt(NH3)2Cl2 that has itself been used as an anticancer drug, cisplatin, since 1978. The disadvantages of such a synthesis of K[Pt(NH3)Cl3] are the aforementioned biological activity of cis Pt(NH3)2Cl2 and very low yields of the key product. Alternative syntheses start from the less biologically active potassium tetrachloridoplatinate(II), K2PtCl4, but yields are lower than for the processes starting from cisplatin. The aim of this work was to find a new synthetic route for the pre (en)
Title
  • Synthesis of Amminetrichloroplatinate(II) Ion
  • Synthesis of Amminetrichloroplatinate(II) Ion (en)
skos:prefLabel
  • Synthesis of Amminetrichloroplatinate(II) Ion
  • Synthesis of Amminetrichloroplatinate(II) Ion (en)
skos:notation
  • RIV/60461373:22310/09:00022471!RIV10-GA0-22310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(2A-2TP1/049), P(GD203/08/H032)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 345094
http://linked.open...ai/riv/idVysledku
  • RIV/60461373:22310/09:00022471
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • platinum complexes; potassium amminetrichloroplatinate (II) (potassium amminetrichloriplatinate (II)); cisplatin; potassium tetrachloroplatinate (II) (tetrachloridoplatinate(II)) (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [CD71E831AABF]
http://linked.open...v/mistoKonaniAkce
  • Porto Carras, Chalkidiki Greece
http://linked.open...i/riv/mistoVydani
  • Thessaloniki
http://linked.open...i/riv/nazevZdroje
  • Clear Summer School
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Kačer, Petr
  • Potucká, Lucie
  • Červený, Libor
  • Kysilka, Vladimír
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
number of pages
http://purl.org/ne...btex#hasPublisher
  • CPERI-CERTH
https://schema.org/isbn
  • 978-960-98231-1-1
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  • 22310
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