About: Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: Is generalization of steatosis accompanied by fibrosis of the liver tissue?     Goto   Sponge   NotDistinct   Permalink

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  • The objective of this work was to study the mechanism of liver parenchyma development under the influence of restriction of diet. Useful information is presented about the pathologic features associated with diet restriction in a chicken animal model of NAFLD. Hepatocyte diameter was significantly influenced by sex, genotype, and the experimental group. The proportion of interstitial tissue to the liver parenchyma was highly influenced by genotype and group, but there were no interactions. An increase in the steatosis histologic grade is associated with inflammatory changes, with decrease of hepatocyte diameter and with a decreasing proportion of interstitial tissue to the liver parenchyma. The results show that early restriction is not associated with the development of fibrosis of the liver tissue.
  • The objective of this work was to study the mechanism of liver parenchyma development under the influence of restriction of diet. Useful information is presented about the pathologic features associated with diet restriction in a chicken animal model of NAFLD. Hepatocyte diameter was significantly influenced by sex, genotype, and the experimental group. The proportion of interstitial tissue to the liver parenchyma was highly influenced by genotype and group, but there were no interactions. An increase in the steatosis histologic grade is associated with inflammatory changes, with decrease of hepatocyte diameter and with a decreasing proportion of interstitial tissue to the liver parenchyma. The results show that early restriction is not associated with the development of fibrosis of the liver tissue. (en)
Title
  • Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: Is generalization of steatosis accompanied by fibrosis of the liver tissue?
  • Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: Is generalization of steatosis accompanied by fibrosis of the liver tissue? (en)
skos:prefLabel
  • Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: Is generalization of steatosis accompanied by fibrosis of the liver tissue?
  • Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: Is generalization of steatosis accompanied by fibrosis of the liver tissue? (en)
skos:notation
  • RIV/60460709:41210/11:50330!RIV12-MSM-41210___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 198819
http://linked.open...ai/riv/idVysledku
  • RIV/60460709:41210/11:50330
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • hyperaemia, lipids, metabolism, NASH, nutrition, restriction, starvation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [C030942C2794]
http://linked.open...i/riv/nazevZdroje
  • Pathology Research and Practice
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 207
http://linked.open...iv/tvurceVysledku
  • Rajmon, Radko
  • Tůmová, Eva
  • Dudová, Markéta
  • Makovický, Peter
  • Vodková, Zuzana
http://linked.open...ain/vavai/riv/wos
  • 0
http://linked.open...n/vavai/riv/zamer
issn
  • 0344-0338
number of pages
http://localhost/t...ganizacniJednotka
  • 41210
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