| Attributes | Values |
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| rdf:type
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| Description
| - After in vitro maturation, the unfertilized pig oocytes underwent the process called aging. This process involves typical events such as fragmentation, spontaneous parthenogenetic activation or lysis. Inhibition of histone deacetylase, using its specific inhibitor trichostatin A (TSA), significantly delayed the maturation of pig oocytes cultured in vitro. The aging of oocytes matured under the effect of TSA is the same as the aging in oocytes matured without TSA. The inhibition of histone deacetylase during oocyte aging significantly reduced the percentage of fragmented oocytes (from 30% in untreated oocytes to 9% in oocytes aged under the effect of 100 nM of TSA). Oocytes matured in vitro and subsequently aged for 1 day under the effects of TSA retained their developmental capacity. After parthenogenetic activation, a significantly higher portion (27% vs. 15%) of oocytes developed to the blastocyst stage after 24hour aging under100 nM TSA when compared to oocytes activated after 24hour aging in a TS
- After in vitro maturation, the unfertilized pig oocytes underwent the process called aging. This process involves typical events such as fragmentation, spontaneous parthenogenetic activation or lysis. Inhibition of histone deacetylase, using its specific inhibitor trichostatin A (TSA), significantly delayed the maturation of pig oocytes cultured in vitro. The aging of oocytes matured under the effect of TSA is the same as the aging in oocytes matured without TSA. The inhibition of histone deacetylase during oocyte aging significantly reduced the percentage of fragmented oocytes (from 30% in untreated oocytes to 9% in oocytes aged under the effect of 100 nM of TSA). Oocytes matured in vitro and subsequently aged for 1 day under the effects of TSA retained their developmental capacity. After parthenogenetic activation, a significantly higher portion (27% vs. 15%) of oocytes developed to the blastocyst stage after 24hour aging under100 nM TSA when compared to oocytes activated after 24hour aging in a TS (en)
- After in vitro maturation, the unfertilized pig oocytes underwent the process called aging. This process involves typical events such as fragmentation, spontaneous parthenogenetic activation or lysis. Inhibition of histone deacetylase, using its specific inhibitor trichostatin A (TSA), significantly delayed the maturation of pig oocytes cultured in vitro. The aging of oocytes matured under the effect of TSA is the same as the aging in oocytes matured without TSA. The inhibition of histone deacetylase during oocyte aging significantly reduced the percentage of fragmented oocytes (from 30% in untreated oocytes to 9% in oocytes aged under the effect of 100 nM of TSA). Oocytes matured in vitro and subsequently aged for 1 day under the effects of TSA retained their developmental capacity. After parthenogenetic activation, a significantly higher portion (27% vs. 15%) of oocytes developed to the blastocyst stage after 24hour aging under100 nM TSA when compared to oocytes activated after 24hour aging in a TS (cs)
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| Title
| - In vitro aging of pig oocytes: effects of the histone deacetylase inhibitor trichostatin A
- n vitro stárnutí prasečích oocytů efekt inhibitoru histon deacetylázy trichostatinu A (cs)
- In vitro aging of pig oocytes: effects of the histone deacetylase inhibitor trichostatin A (en)
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| skos:prefLabel
| - In vitro aging of pig oocytes: effects of the histone deacetylase inhibitor trichostatin A
- n vitro stárnutí prasečích oocytů efekt inhibitoru histon deacetylázy trichostatinu A (cs)
- In vitro aging of pig oocytes: effects of the histone deacetylase inhibitor trichostatin A (en)
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| skos:notation
| - RIV/60460709:41210/08:26239!RIV09-MZE-41210___
|
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(QD0085), P(QG50052), Z(MSM6046070901)
|
| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/60460709:41210/08:26239
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - oocyte; aging; histone deacetylase; trichostatin A; pig (en)
|
| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
|
| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Jílek, František
- Petr, Jaroslav
- Ješeta, Michal
- Chmelíková, Eva
- Krejčová, Tereza
|
| http://linked.open...n/vavai/riv/zamer
| |
| issn
| |
| number of pages
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| http://localhost/t...ganizacniJednotka
| |
| is http://linked.open...avai/riv/vysledek
of | |
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