About: The influence of biochanin A on the meiotic maturation of pig oocytes

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Phytoestrogens are natural plant substances structurally similar to endogenous estrogens. There is evidence, that they influence the maturation of mammalian oocytes. Although biochanin A is one of the first phytoestrogens connected with reproductive disorders, there are no data about its influence on oocytes. The aim of our study was to verify biochanin A effects on the meiotic maturation of pig oocytes. Oocytes were cultivated for 24 hours to the MI stage of meiotic maturation. Various amounts of biochanin A (0, 20, 30, 40, 50, 60, 80 ug/ml) were added to the medium. Biochanin A inhibited pig oocyte maturation before germinal vesicle breakdown (GVBD) in a dose-dependent manner. The addition of 80 and 60 ug/ml of biochanin A already acted toxically. Phytoestrogens are natural plant substances structurally similar to endogenous estrogens. There is evidence, that they influence the maturation of mammalian oocytes. Although biochanin A is one of the first phytoestrogens connected with reproductive disorders, there are no data about its influence on oocytes. The aim of our study was to verify biochanin A effects on the meiotic maturation of pig oocytes. Oocytes were cultivated for 24 hours to the MI stage of meiotic maturation. Various amounts of biochanin A (0, 20, 30, 40, 50, 60, 80 ug/ml) were added to the medium. Biochanin A inhibited pig oocyte maturation before germinal vesicle breakdown (GVBD) in a dose-dependent manner. The addition of 80 and 60 ug/ml of biochanin A already acted toxically. (en) Phytoestrogens are natural plant substances structurally similar to endogenous estrogens. There is evidence, that they influence the maturation of mammalian oocytes. Although biochanin A is one of the first phytoestrogens connected with reproductive disorders, there are no data about its influence on oocytes. The aim of our study was to verify biochanin A effects on the meiotic maturation of pig oocytes. Oocytes were cultivated for 24 hours to the MI stage of meiotic maturation. Various amounts of biochanin A (0, 20, 30, 40, 50, 60, 80 ug/ml) were added to the medium. Biochanin A inhibited pig oocyte maturation before germinal vesicle breakdown (GVBD) in a dose-dependent manner. The addition of 80 and 60 ug/ml of biochanin A already acted toxically. (cs)
Title	The influence of biochanin A on the meiotic maturation of pig oocytes The influence of biochanin A on the meiotic maturation of pig oocytes (en) Vliv biochaninu A na meiotické zrání oocytů prasete (cs)
skos:prefLabel	The influence of biochanin A on the meiotic maturation of pig oocytes The influence of biochanin A on the meiotic maturation of pig oocytes (en) Vliv biochaninu A na meiotické zrání oocytů prasete (cs)
skos:notation	RIV/60460709:41210/05:###11694!RIV06-MZE-41210___
http://linked.open.../vavai/riv/strany	29;30
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GD523/03/H076), P(QF3025), Z(MSM6046070901)
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Ješeta, Michal Rajmon, Radko Vodková, Zuzana Petr, Jaroslav Chmelíková, Eva
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Česká zemědělská univerzita v Praze / Fakulta agrobiologie, potravinových a přírodních zdrojů
http://linked.open...dnocenehoVysledku	524640
http://linked.open...ai/riv/idVysledku	RIV/60460709:41210/05:###11694
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	pig, oocyte, meiosis, phytoestrogens, biochanin A (en)
http://linked.open.../riv/klicoveSlovo	phytoestrogens biochanin A oocyte pig meiosis
http://linked.open...ontrolniKodProRIV	[9E5AF33BEBB7]
http://linked.open...v/mistoKonaniAkce	České Budějovice
http://linked.open...i/riv/mistoVydani	České Budějovice
http://linked.open...i/riv/nazevZdroje	Journal of Applied Biomedicine
http://linked.open...in/vavai/riv/obor	GG
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Substances with estrogenic effects in food chains, impacts on health and yield of domestic animals and foodstuff safety Enhancing of Methodological Level and Theoretical Education of Students of the Ph. D. Program 4103V - Animal Husbandry - a Perspective Field General Animal Husb
http://linked.open...UplatneniVysledku	2005
http://linked.open...iv/tvurceVysledku	Petr, Jaroslav Rajmon, Radko Ješeta, Michal Chmelíková, Eva Kuthanová, Zuzana
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2005-10-24 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Setrvalé zemědělství, kvalita zemědělské produkce, krajinné a přírodní zdroje.
issn	1214-0287
number of pages	2 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Biologická fakulta
http://localhost/t...ganizacniJednotka	41210
is http://linked.open...avai/riv/vysledek of	The influence of biochanin A on the meiotic maturation of pig oocytes

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