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| rdfs:seeAlso
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| Description
| - The genus Enterococcus is represented by some of the clinically important species and is well known for its antibiotic resistance, which participates in colonization and infection. Increasing resistance of enterococci has been evoked due to the excessive use of antibotics not merely for therapeutic purposes or indicated cases. One of the promising possibilities how to reduce the use of great amount of antibiotics is to utilize antimicrobial properties of natural substances. Usnic acid is a lichem compound possessing antibacterial activity against gramůpositive bacteria including enterococci. Octyl gallate, gallic acid ester, has significant antibacterial and antifungal properties. This study was focused on the evaluation of resistant enterococci susceptibility to usnic acid and octyl gallate in comparison with control group of enterococci. Antibacterial activity of usnic acid and octyl gallate was defined as minimum inhibitory concentration and minum bactericidal concentration,. Usnic acid inhibited all tested enerococci in concentration range 4.7-37.5 mg.L-1. MIC values of octyl gallate for all tested enterococci ranged between 37.5-150 mg.L-1. In contrast to octyl gallate, bactericidal activity of usnic acid was not confirmed. Antibacterial activities of tested compounds were almost equal among resistant enterococci and control group of enterococci exibiting great potential of usnic acid and octyl gallate for tretment of enterococcal infections.
- The genus Enterococcus is represented by some of the clinically important species and is well known for its antibiotic resistance, which participates in colonization and infection. Increasing resistance of enterococci has been evoked due to the excessive use of antibotics not merely for therapeutic purposes or indicated cases. One of the promising possibilities how to reduce the use of great amount of antibiotics is to utilize antimicrobial properties of natural substances. Usnic acid is a lichem compound possessing antibacterial activity against gramůpositive bacteria including enterococci. Octyl gallate, gallic acid ester, has significant antibacterial and antifungal properties. This study was focused on the evaluation of resistant enterococci susceptibility to usnic acid and octyl gallate in comparison with control group of enterococci. Antibacterial activity of usnic acid and octyl gallate was defined as minimum inhibitory concentration and minum bactericidal concentration,. Usnic acid inhibited all tested enerococci in concentration range 4.7-37.5 mg.L-1. MIC values of octyl gallate for all tested enterococci ranged between 37.5-150 mg.L-1. In contrast to octyl gallate, bactericidal activity of usnic acid was not confirmed. Antibacterial activities of tested compounds were almost equal among resistant enterococci and control group of enterococci exibiting great potential of usnic acid and octyl gallate for tretment of enterococcal infections. (en)
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| Title
| - In vitro antibacterial activity of usnic acid and octyl gallate against resistant enterococcus strains
- In vitro antibacterial activity of usnic acid and octyl gallate against resistant enterococcus strains (en)
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| skos:prefLabel
| - In vitro antibacterial activity of usnic acid and octyl gallate against resistant enterococcus strains
- In vitro antibacterial activity of usnic acid and octyl gallate against resistant enterococcus strains (en)
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| skos:notation
| - RIV/60162694:G44__/14:43875235!RIV15-MO0-G44_____
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/60162694:G44__/14:43875235
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - MBC; MIC; usnic acid; octyl gallate; enterococci (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Military Medical Science Letters
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Boštíková, Vanda
- Mazurová, Jaroslava
- Kukla, Rudolf
- Sleha, Radek
- Slehová, Eva
- Adámková, Vaclava
- Janovska, Sylva
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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