About: Hydrolysis of carboxylate and phosphate esters using monopyridinium oximes in cationic micellar media

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Hydrolysis of carboxylate and phosphate esters using monopyridinium oximes in cationic micellar media Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1002/kin.20590
Description	The reactions of p-nitrophenyl acetate (PNPA) with a series of monopyridinium oximes, viz. 2-PAM (2-hydroxyiminomethyl-1-methylpyridinium iodide), 3-PAM (3-hydroxyiminomethyl-1-methylpyridinium iodide), and 4-PAM (4-hydroxyiminomethyl-1-methylpyridinium iodide) have been studied in the presence of cationic surfactants of same hydrophobic chain length (C(16)) within the concentration range of 0.5-6.0 mM at pH 8.0 under the pseudo-first-order condition. The observed rate constant (k(obs)) increases with increasing surfactant concentration culminating into a maximum, and this has been analyzed in detail following the concepts of micellar catalysis. The structure-activity relationship of the investigated oximes has been discussed, and 2-PAM was found to be the most reactive among all the three investigated oximes for the cleavage of PNPA. Esterolytic decomposition of p-nitrophenyldiphenyl phosphate with oximate ions (-CH=NO(-)) was followed in cetyltrimethylammonium bromide micelles at pH 9.0, and 4-PAM was the most reactive oxime for the micellar hydrolysis of phosphate ester. The apparent acid dissociation constants (pK(a)) of the investigated oximes have been determined spectrophotometrically. The reactions of p-nitrophenyl acetate (PNPA) with a series of monopyridinium oximes, viz. 2-PAM (2-hydroxyiminomethyl-1-methylpyridinium iodide), 3-PAM (3-hydroxyiminomethyl-1-methylpyridinium iodide), and 4-PAM (4-hydroxyiminomethyl-1-methylpyridinium iodide) have been studied in the presence of cationic surfactants of same hydrophobic chain length (C(16)) within the concentration range of 0.5-6.0 mM at pH 8.0 under the pseudo-first-order condition. The observed rate constant (k(obs)) increases with increasing surfactant concentration culminating into a maximum, and this has been analyzed in detail following the concepts of micellar catalysis. The structure-activity relationship of the investigated oximes has been discussed, and 2-PAM was found to be the most reactive among all the three investigated oximes for the cleavage of PNPA. Esterolytic decomposition of p-nitrophenyldiphenyl phosphate with oximate ions (-CH=NO(-)) was followed in cetyltrimethylammonium bromide micelles at pH 9.0, and 4-PAM was the most reactive oxime for the micellar hydrolysis of phosphate ester. The apparent acid dissociation constants (pK(a)) of the investigated oximes have been determined spectrophotometrically. (en)
Title	Hydrolysis of carboxylate and phosphate esters using monopyridinium oximes in cationic micellar media Hydrolysis of carboxylate and phosphate esters using monopyridinium oximes in cationic micellar media (en)
skos:prefLabel	Hydrolysis of carboxylate and phosphate esters using monopyridinium oximes in cationic micellar media Hydrolysis of carboxylate and phosphate esters using monopyridinium oximes in cationic micellar media (en)
skos:notation	RIV/60162694:G44__/11:00002475!RIV12-MO0-G44_____
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(OVUOFVZ200803)
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kuča, Kamil Marek, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	203143
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/11:00002475
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	in-vitro; acetylcholinesterase reactivators; nucleophilic-substitution; nerve agents; pralidoxime; systems; acceleration; assemblies; reactivity; catalysis (en)
http://linked.open.../riv/klicoveSlovo	pralidoxime catalysis nerve agents systems reactivity acceleration acetylcholinesterase reactivators assemblies in-vitro nucleophilic-substitution
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[7F0A726376CE]
http://linked.open...i/riv/nazevZdroje	International Journal of Chemical Kinetics
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Development of novel decontaminants and disinfectants of skin based on micellar compounds
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	43
http://linked.open...iv/tvurceVysledku	Kuča, Kamil Marek, Jan Ghosh, Kallol K Singh, Namrata
http://linked.open...ain/vavai/riv/wos	000294225300006
issn	0538-8066
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	G44
is http://linked.open...avai/riv/vysledek of	Hydrolysis of carboxylate and phosphate esters using monopyridinium oximes in cationic micellar media

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 35 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software