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  • During the last two decades, the treatment of organophosphate pesticide (OPP) exposure became more discussed regarding the growing agricultural production, industrial and suicidal means. In this chapter is summarised the design, evaluation and structure-activity relationship studies of recently produced AChE reactivators. Since pralidoxime, many oximes have been produced or tested against OPP poisoning, and several novel compounds show very promising abilities as comparable (or higher) to commercial oximes. Some of these are highlighted for their further testing of OPP exposure, and additionally, the main structure-activity relationship of AChE reactivators against OPP are discussed.
  • During the last two decades, the treatment of organophosphate pesticide (OPP) exposure became more discussed regarding the growing agricultural production, industrial and suicidal means. In this chapter is summarised the design, evaluation and structure-activity relationship studies of recently produced AChE reactivators. Since pralidoxime, many oximes have been produced or tested against OPP poisoning, and several novel compounds show very promising abilities as comparable (or higher) to commercial oximes. Some of these are highlighted for their further testing of OPP exposure, and additionally, the main structure-activity relationship of AChE reactivators against OPP are discussed. (en)
Title
  • Progress in antidotes (acetylcholinesterase reactivators) against organophosphorus pesticides
  • Progress in antidotes (acetylcholinesterase reactivators) against organophosphorus pesticides (en)
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  • Progress in antidotes (acetylcholinesterase reactivators) against organophosphorus pesticides
  • Progress in antidotes (acetylcholinesterase reactivators) against organophosphorus pesticides (en)
skos:notation
  • RIV/60162694:G44__/11:00002448!RIV12-MSM-G44_____
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(ME09086)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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  • 224467
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G44__/11:00002448
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  • acetylcholinesterase; pesticide; insecticide; reactivation; oxime; SAR (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [528728FBDD18]
http://linked.open...i/riv/mistoVydani
  • Rijeka
http://linked.open...i/riv/nazevZdroje
  • Pesticides in the modern world - Effects of pesticides exposure
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Kuča, Kamil
  • Musílek, Kamil
  • Pohanka, Miroslav
  • Žďárová Karasová, Jana
  • Jun, Daniel
  • Holas, Ondřej
  • Horová, Anna
number of pages
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  • Intech
https://schema.org/isbn
  • 978-953-307-454-2
http://localhost/t...ganizacniJednotka
  • G44
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