About: Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs

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About: Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of this study was to evaluate the diagnostic yield of capsule endoscopy in nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy in pigs. Indomethacin (400 mg/day) was administered orally for 10 days to eight female pigs. Afterwards, capsule endoscopy was performed, using the EndoCapsule system (OlympusOpticalCo., Tokyo, Japan). The following morning, pharmacological euthanasia and immediate autopsy were performed. Small bowel injury compatible with NSAID-induced enteropathy was observed in 7/8 animals. The most common lesions were red spots and erosions. Ulcers and small intestinal bleeding were identified sporadically. Sensitivity and specificity of capsule endoscopy were 83.3% and 95.8%, respectively. Our results indicate that wireless capsule endoscopy is a highly accurate noninvasive method for evaluation of experimental NSAID-induced enteropathy.10.1007/s10620-009-1066-z The aim of this study was to evaluate the diagnostic yield of capsule endoscopy in nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy in pigs. Indomethacin (400 mg/day) was administered orally for 10 days to eight female pigs. Afterwards, capsule endoscopy was performed, using the EndoCapsule system (OlympusOpticalCo., Tokyo, Japan). The following morning, pharmacological euthanasia and immediate autopsy were performed. Small bowel injury compatible with NSAID-induced enteropathy was observed in 7/8 animals. The most common lesions were red spots and erosions. Ulcers and small intestinal bleeding were identified sporadically. Sensitivity and specificity of capsule endoscopy were 83.3% and 95.8%, respectively. Our results indicate that wireless capsule endoscopy is a highly accurate noninvasive method for evaluation of experimental NSAID-induced enteropathy.10.1007/s10620-009-1066-z (en)
Title	Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs (en)
skos:prefLabel	Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs (en)
skos:notation	RIV/60162694:G44__/10:00002409!RIV11-MO0-G44_____
http://linked.open...avai/riv/aktivita	I P V Z
http://linked.open...avai/riv/aktivity	I, P(GA305/08/0535), V, Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Pejchal, Jaroslav Špelda, Stanislav Österreicher, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	298865
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/10:00002409
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	experimental pigs; enteroscopy; capsule endoscopy; nonsteroidal anti-inflammatory drugs; indomethacin; NSAID-induced enteropathy (en)
http://linked.open.../riv/klicoveSlovo	nonsteroidal anti-inflammatory drugs capsule endoscopy experimental pigs indomethacin enteroscopy NSAID-induced enteropathy
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[50F03CB02EDC]
http://linked.open...i/riv/nazevZdroje	Digestive Diseases and Sciences
http://linked.open...in/vavai/riv/obor	FE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Interference of probiotics with factors determining pharmacokinetics of drugs
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	55
http://linked.open...iv/tvurceVysledku	Bureš, Jan Kuneš, Martin Květina, Jaroslav Pejchal, Jaroslav Tachecí, Ilja Kopáčová, M. Österreicher, Jan Špelda, Stanislav Reichert, Stanislav
http://linked.open...ain/vavai/riv/wos	000280595500008
http://linked.open...n/vavai/riv/zamer	Nové diagnostické indikátory a léčebné postupy v závislosti na různých obdobích života s důrazem na stáří
issn	0163-2116
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	G44
is http://linked.open...avai/riv/vysledek of	Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs

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