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  • There is no single acetylcholinesterase reactivator for the treatment of various nerve agent or pesticide poisoning. Consequently, there is a demand for the development of a universal so-called broad-spectrum reactivator. Unfortunately, such reactivator was not prepared yet. The relationship between chemical structure of currently available oximes and their reactivation activity should be known to design such reactivator. Particularly, the reactivator´s structuralrequirements needed for the sufficient reactivation process have to be summarized.
  • There is no single acetylcholinesterase reactivator for the treatment of various nerve agent or pesticide poisoning. Consequently, there is a demand for the development of a universal so-called broad-spectrum reactivator. Unfortunately, such reactivator was not prepared yet. The relationship between chemical structure of currently available oximes and their reactivation activity should be known to design such reactivator. Particularly, the reactivator´s structuralrequirements needed for the sufficient reactivation process have to be summarized. (en)
Title
  • Structure-activity relationship of acetylcholinesterase reactivators
  • Structure-activity relationship of acetylcholinesterase reactivators (en)
skos:prefLabel
  • Structure-activity relationship of acetylcholinesterase reactivators
  • Structure-activity relationship of acetylcholinesterase reactivators (en)
skos:notation
  • RIV/60162694:G44__/09:00002248!RIV11-GA0-G44_____
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GP305/07/P162)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 344227
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G44__/09:00002248
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Acetylcholinesterase; nerve agents; reactivator; oxime (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [2AFFF27BB987]
http://linked.open...i/riv/mistoVydani
  • Kerala
http://linked.open...i/riv/nazevZdroje
  • Central and peripheral nervous system: effects of highly toxic organophosphates and their antidotes
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Bajgar, Jiří
  • Kuča, Kamil
  • Marek, Jan
  • Musílek, Kamil
  • Pohanka, Miroslav
  • Jun, Daniel
number of pages
http://purl.org/ne...btex#hasPublisher
  • Research Signpost
https://schema.org/isbn
  • 978-81-308-0331-9
http://localhost/t...ganizacniJednotka
  • G44
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