About: 10-valent pneumococcal nontypeable Haemophilus influenzae PD conjugate vaccine: Synflorix(TM)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The global burden of disease due to Streptococcus pneumoniae remains high. The licensed 7-valent pneumococcal conjugate vaccine (7vCRM, Prevenar(TM)/Prevnar(TM)) has successfully reduced invasive disease in the USA, but serotype coverage is incomplete and some evidence suggests that serotype replacement has occurred. Recently, a new 10-valent pneumococcal nontypeable Haemophilus influenzae (NTHi) protein D (PD) conjugate vaccine (PHiD-CV, Synflorix(TM)) has been licensed in more than 40 countries, including Europe, for the prevention of invasive disease and acute otitis media (AOM) due to pneumococcus in infants and children. PHiD-CV is immunogenic in infants when administered as a three-dose primary vaccination in a range of schedules and has a safety profile comparable to that of 7vCRM. Additional serotypes in PHiD-CV (1, 5 and 7F) increase overall serotype coverage and improve coverage in specific age groups and against specific disease syndromes. The use of the PD carrier, which provided protectio The global burden of disease due to Streptococcus pneumoniae remains high. The licensed 7-valent pneumococcal conjugate vaccine (7vCRM, Prevenar(TM)/Prevnar(TM)) has successfully reduced invasive disease in the USA, but serotype coverage is incomplete and some evidence suggests that serotype replacement has occurred. Recently, a new 10-valent pneumococcal nontypeable Haemophilus influenzae (NTHi) protein D (PD) conjugate vaccine (PHiD-CV, Synflorix(TM)) has been licensed in more than 40 countries, including Europe, for the prevention of invasive disease and acute otitis media (AOM) due to pneumococcus in infants and children. PHiD-CV is immunogenic in infants when administered as a three-dose primary vaccination in a range of schedules and has a safety profile comparable to that of 7vCRM. Additional serotypes in PHiD-CV (1, 5 and 7F) increase overall serotype coverage and improve coverage in specific age groups and against specific disease syndromes. The use of the PD carrier, which provided protectio (en)
Title	10-valent pneumococcal nontypeable Haemophilus influenzae PD conjugate vaccine: Synflorix(TM) 10-valent pneumococcal nontypeable Haemophilus influenzae PD conjugate vaccine: Synflorix(TM) (en)
skos:prefLabel	10-valent pneumococcal nontypeable Haemophilus influenzae PD conjugate vaccine: Synflorix(TM) 10-valent pneumococcal nontypeable Haemophilus influenzae PD conjugate vaccine: Synflorix(TM) (en)
skos:notation	RIV/60162694:G44__/09:00002190!RIV10-MO0-G44_____
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MO0FVZ0000502)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Prymula, Roman
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	353786
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/09:00002190
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	booster immunization; Haemophilus influenzae; immunization; otitis; pneumococcal conjugate vaccine; Streptococcus pneumoniae (en)
http://linked.open.../riv/klicoveSlovo	Streptococcus pneumoniae booster immunization pneumococcal conjugate vaccine immunization otitis Haemophilus influenzae
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[CF7BE011550E]
http://linked.open...i/riv/nazevZdroje	Expert Review of Vaccines
http://linked.open...in/vavai/riv/obor	FN
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	8
http://linked.open...iv/tvurceVysledku	Prymula, Roman Schuerman, Lode
http://linked.open...ain/vavai/riv/wos	000271515500009
http://linked.open...n/vavai/riv/zamer	Implementation of the new information of hygiene, preventive medicine and epidemiology into the military health care
issn	1476-0584
number of pages	22 (xsd:int)
http://localhost/t...ganizacniJednotka	G44
is http://linked.open...avai/riv/vysledek of	10-valent pneumococcal nontypeable Haemophilus influenzae PD conjugate vaccine: Synflorix(TM)

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