| Attributes | Values |
|---|
| rdf:type
| |
| Description
| - This randomized (1:1), double-blind, multicenter study, included 4,968 healthy infants to receive either the 11-valent pneumococcal protein D (PD)-conjugate study vaccine or the hepatitis A vaccine (HAV) (control) at 3, 4, 5, and 12-15 months of age. The three-dose primary course of both vaccines was co-administered with combined hexavalent DTPa-HBV-IPV/Hib vaccine. The pneumococcal PD-conjugate study vaccine did not impact the immune response of co-administered hexavalent vaccine and the control HAV vaccine induced seropositivity (antibodies >or=15 mIU/mL) in all infants. The incidence of solicited symptoms was higher with the 11-valent pneumococcal PD-conjugate study vaccine, yet similar to that induced by concomitant DTPa-HBV-IPV/Hib vaccine. Overall, the reactogenicity and safety profile of the 11-valent pneumococcal PD-conjugate vaccine when co-administered with the hexavalent DTPa-HBV-IPV/Hib vaccine, as well as the immunogenicity of the co-administered hexavalent vaccine, were consistent wit
- This randomized (1:1), double-blind, multicenter study, included 4,968 healthy infants to receive either the 11-valent pneumococcal protein D (PD)-conjugate study vaccine or the hepatitis A vaccine (HAV) (control) at 3, 4, 5, and 12-15 months of age. The three-dose primary course of both vaccines was co-administered with combined hexavalent DTPa-HBV-IPV/Hib vaccine. The pneumococcal PD-conjugate study vaccine did not impact the immune response of co-administered hexavalent vaccine and the control HAV vaccine induced seropositivity (antibodies >or=15 mIU/mL) in all infants. The incidence of solicited symptoms was higher with the 11-valent pneumococcal PD-conjugate study vaccine, yet similar to that induced by concomitant DTPa-HBV-IPV/Hib vaccine. Overall, the reactogenicity and safety profile of the 11-valent pneumococcal PD-conjugate vaccine when co-administered with the hexavalent DTPa-HBV-IPV/Hib vaccine, as well as the immunogenicity of the co-administered hexavalent vaccine, were consistent wit (en)
- Tato randomizovaná (1:1) dvojitě slepá, multicentrická studie, zahrnovala 4968 zdravých kojenců, kteří obdrželi buď 11ti valentní penumokokovou konjugovanou vakcínu na protein D (PD) nebo vakcín proti hepatitidě A (HAV) (kontrola) v měsíci 3, 4, 5 a 12-15. Tří-dávkové primární schéma obou vakcín bylo koadministrováno s kombinovanou hexavalentní vakcínou TTPa - HPV - IPV/Hib. Pneumokoková konjugovaná vakcína na PD neovlivnila imunitní odpověď spolupodané hexavalentní vakcíny a kontrolní vakcínou proti HAV indukovanou seropozitivitu (protilátky větší nebo rovno 15 mIU/mL) u žádného dítěte. Incidence vybraných simptomů byla vyšší u 11ti valentní penumokokové konjugované vakcíny na PD i když podobná incidenci indukované spolupodanou vakcínou proti TTPa - HPV - IPV/Hib. Celkově reaktogenita a bezpečnostní profil 11ti valentní pneumokokové konjugované PD vakcíny, když je spolupodána hexavalentní TTPa - HPV - IPV/Hib vakcínou, jakož i imunogenita spolupodané hexavalentní vakcíny byla konzistentní s předcháze (cs)
|
| Title
| - Safety of the 11-valent pneumococcal vaccine conjugated to non-typeable Haemophilus influenzae-derived protein D in the first 2 years of life and immunogenicity of the co-administered dexavalent diphtheria, tetanus, acellular pertussis, hepatits B
- Bezpečnost 11valentní pneumokokové vakcíny konjugované na D protein derivovaný z netypovatelných haemophylus influenzae v prvních dvou letech života a imunogenita spolupodané hexavalentní vakcíny proti diftérii tetanu acelulární pertusi hepatitis B in (cs)
- Safety of the 11-valent pneumococcal vaccine conjugated to non-typeable Haemophilus influenzae-derived protein D in the first 2 years of life and immunogenicity of the co-administered dexavalent diphtheria, tetanus, acellular pertussis, hepatits B (en)
|
| skos:prefLabel
| - Safety of the 11-valent pneumococcal vaccine conjugated to non-typeable Haemophilus influenzae-derived protein D in the first 2 years of life and immunogenicity of the co-administered dexavalent diphtheria, tetanus, acellular pertussis, hepatits B
- Bezpečnost 11valentní pneumokokové vakcíny konjugované na D protein derivovaný z netypovatelných haemophylus influenzae v prvních dvou letech života a imunogenita spolupodané hexavalentní vakcíny proti diftérii tetanu acelulární pertusi hepatitis B in (cs)
- Safety of the 11-valent pneumococcal vaccine conjugated to non-typeable Haemophilus influenzae-derived protein D in the first 2 years of life and immunogenicity of the co-administered dexavalent diphtheria, tetanus, acellular pertussis, hepatits B (en)
|
| skos:notation
| - RIV/60162694:G44__/08:00001959!RIV09-MO0-G44_____
|
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| |
| http://linked.open...iv/cisloPeriodika
| |
| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/60162694:G44__/08:00001959
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - Pneumococcal protein D; conjugate/DTPa-HBV-IPV/Hib combination; vaccines; immunogenicity (en)
|
| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
|
| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Chlíbek, Roman
- Špliňo, Miroslav
- Kalíšková, Eva
- Lommel, Patricia
- Prymula, Roman
- Kohl, Igor
- Schuerman, lode
|
| http://linked.open...ain/vavai/riv/wos
| |
| http://linked.open...n/vavai/riv/zamer
| |
| issn
| |
| number of pages
| |
| http://localhost/t...ganizacniJednotka
| |
| is http://linked.open...avai/riv/vysledek
of | |
![[RDF Data]](/fct/images/sw-rdf-blue.png)
![[cxml]](/fct/images/cxml_doc.png)
![[csv]](/fct/images/csv_doc.png)
![[text]](/fct/images/ntriples_doc.png)
![[turtle]](/fct/images/n3turtle_doc.png)
![[ld+json]](/fct/images/jsonld_doc.png)
![[rdf+json]](/fct/images/json_doc.png)
![[rdf+xml]](/fct/images/xml_doc.png)
![[atom+xml]](/fct/images/atom_doc.png)
![[html]](/fct/images/html_doc.png)