About: In vitro and in vivo metabolisms of K-48     Goto   Sponge   NotDistinct   Permalink

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  • Metabolic pathways of the oxime K-48 have been elucidated by means of in vitro and in vivo experiments. K-48 exposure to rat liver microsomal fraction resulted in the formation of a hydroxylated derivative, in addition to a small molecular fragment. The in vivo metabolism in rats was investigated after intramuscular administration of 50 μmol oxime. K-48 was present in the rat serum in unchanged form.
  • Metabolic pathways of the oxime K-48 have been elucidated by means of in vitro and in vivo experiments. K-48 exposure to rat liver microsomal fraction resulted in the formation of a hydroxylated derivative, in addition to a small molecular fragment. The in vivo metabolism in rats was investigated after intramuscular administration of 50 μmol oxime. K-48 was present in the rat serum in unchanged form. (en)
Title
  • In vitro and in vivo metabolisms of K-48
  • In vitro and in vivo metabolisms of K-48 (en)
skos:prefLabel
  • In vitro and in vivo metabolisms of K-48
  • In vitro and in vivo metabolisms of K-48 (en)
skos:notation
  • RIV/60162694:G44__/07:00001822!RIV10-MO0-G44_____
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • N
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 425848
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G44__/07:00001822
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • microsomal metabolism; cholinesterase reactivator; K-48; in vivo metabolism; HPLC-MS (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [1889857FBB3D]
http://linked.open...i/riv/nazevZdroje
  • Analytical and Bioanalytical Chemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 389
http://linked.open...iv/tvurceVysledku
  • Kuča, Kamil
  • Kalasz, H.
  • Petroianu, G.
  • Ludányi, K.
  • Benko, B.
http://linked.open...ain/vavai/riv/wos
  • 000249729400026
issn
  • 1618-2642
number of pages
http://localhost/t...ganizacniJednotka
  • G44
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