About: Molecular cloning, structure and bait region splice variants of alpha-2-macroglobulin from the soft tick Ornithodoros moubata     Goto   Sponge   NotDistinct   Permalink

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Description
  • Klíštěcí ?-makroglobulin (TAM) je prvním reprezentantem proteinové rodiny ?2-makroglobulinů (?2-M, univerzální inhibitory proteáz) popsaným u suchozemských členovců. Byla určena primární struktura TAM (1494 aminokyselin) a porovnána s ?2-M ostatních obratlovců i bezobratlých. Klíštěcí TAM je na rozdíl od ostatních ?2-M postranslačně rozdělen na dvě podjednotky a jeho „návnadová doména“ (štěpená cílovou proteázou) je přítomna v nejméně čtyřech variantách vzniklých alternativním sestřihem (cs)
  • Tick ?2-macroglobulin (TAM) is the first representative of ?2-macroglobulin family (?2-M, universal protease inhibitor) described among terrestrial arthropods. The primary structure of TAM was determined (1494 amino-acid residues) and compared to ?2-Ms from vertebrates and invertebrates. Unlike other known ?2-Ms, TAM is post-translationally cleaved into two subunits and possesses at least four splicing variants of the „bait region“ which is cleaved by the targeting proteases
  • Tick ?2-macroglobulin (TAM) is the first representative of ?2-macroglobulin family (?2-M, universal protease inhibitor) described among terrestrial arthropods. The primary structure of TAM was determined (1494 amino-acid residues) and compared to ?2-Ms from vertebrates and invertebrates. Unlike other known ?2-Ms, TAM is post-translationally cleaved into two subunits and possesses at least four splicing variants of the „bait region“ which is cleaved by the targeting proteases (en)
Title
  • Molekulární klonování, struktura a alternativní sestřih „návnadové domény“ ?2-makroglobulinu z klíšťáka Ornithodros moubata (cs)
  • Molecular cloning, structure and bait region splice variants of alpha-2-macroglobulin from the soft tick Ornithodoros moubata
  • Molecular cloning, structure and bait region splice variants of alpha-2-macroglobulin from the soft tick Ornithodoros moubata (en)
skos:prefLabel
  • Molekulární klonování, struktura a alternativní sestřih „návnadové domény“ ?2-makroglobulinu z klíšťáka Ornithodros moubata (cs)
  • Molecular cloning, structure and bait region splice variants of alpha-2-macroglobulin from the soft tick Ornithodoros moubata
  • Molecular cloning, structure and bait region splice variants of alpha-2-macroglobulin from the soft tick Ornithodoros moubata (en)
skos:notation
  • RIV/60077409:_____/03:00157647!RIV06-AV0-60077409
http://linked.open.../vavai/riv/strany
  • 841;851
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA206/00/0266), P(IAA6022307), Z(AV0Z6022909)
http://linked.open...iv/cisloPeriodika
  • 8
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 616264
http://linked.open...ai/riv/idVysledku
  • RIV/60077409:_____/03:00157647
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Ornithodoros moubata; innate immunity; alpha-2-macroglobulin (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [79AA1E684F89]
http://linked.open...i/riv/nazevZdroje
  • Insect Biochemistry and Molecular Biology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 33
http://linked.open...iv/tvurceVysledku
  • Kopáček, Petr
  • Sojka, D.
  • Weise, C.
  • Saravanan, Thangamani
http://linked.open...n/vavai/riv/zamer
issn
  • 0965-1748
number of pages
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