About: Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs

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About: Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Metabolism of paclitaxel and docetaxel of cytochrome P450 was compared in humans, pigs, minipigs and rats. While docetaxel metabolism is the same in all four compared species, metabolism of paclitaxel showed differences, especially in 6alpha-hydroxypaclitaxel present exclusively in humans. Metabolism of paclitaxel and docetaxel of cytochrome P450 was compared in humans, pigs, minipigs and rats. While docetaxel metabolism is the same in all four compared species, metabolism of paclitaxel showed differences, especially in 6alpha-hydroxypaclitaxel present exclusively in humans. (en) Byl porovnán metabolismus paclitaxelu a docetaxelu cytochromy P450 u člověka, prasete, miniprasete a krysy. Zatímco metabolismus docetaxelu je stejný u všech čtyř zkoumaných druhů, metabolismus paclitaxelu vykazuje rozdíly, zejména v 6?-hydroxypaclitaxelu přítomnému výlučně u člověka. (cs)
Title	Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs (en) Rozdílný metabolismus paclitaxelu a docetaxelu u člověka, krysy, prasete a minprasete (cs)
skos:prefLabel	Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs (en) Rozdílný metabolismus paclitaxelu a docetaxelu u člověka, krysy, prasete a minprasete (cs)
skos:notation	RIV/60077395:_____/04:00100912!RIV/2005/AV0/A60005/N
http://linked.open.../vavai/riv/strany	666;674
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/02/1152), P(NL6715), P(NL7567), Z(AV0Z5007907)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Šimek, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Entomologický ústav AV ČR
http://linked.open...dnocenehoVysledku	560557
http://linked.open...ai/riv/idVysledku	RIV/60077395:_____/04:00100912
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	human-liver microsomes;human cytochromes P450 (en)
http://linked.open.../riv/klicoveSlovo	human cytochromes P450 human-liver microsomes
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[EED831EEC236]
http://linked.open...i/riv/nazevZdroje	Drug Metabolism and Disposition
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Mechanisms of resistance of tumor cells lines and breast cancer to chemotherapy by taxanes and possibilities of intervention Effect of polyphenols and chelators on toxicity and effects of anthracyclines and taxanes Structure and function of cytochromes P450 of human and (mini)pig origin
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	32
http://linked.open...iv/tvurceVysledku	Šimek, Petr Souček, P. Anzenbacher, P. Svobodová, L. Gut, I. Václavíková, R. Guengerich, F. P.
http://linked.open...n/vavai/riv/zamer	The use of insects for quality assessment and possible management of the ecosystems in Central Europe
issn	0090-9556
number of pages	9 (xsd:int)

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