About: (Self-) infections with parasites: re-interpretations for the present

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Previously, scientists sometimes resorted to infecting themselves or colleagues with parasites, usually to assess the pathogenicity and obtain insight into the life cycles of the parasites, host specificity, and epidemiology. However, with recent research addressing the possible beneficial impact of intestinal helminths on a range of immune-mediated diseases in humans, these studies offer valuable information, although many are now considered unethical owing to a lack of experimental oversight and informed consent. Here, we critically review cases in which humans were deliberately infected with parasites. Moreover, we summarize the contribution of (self-) infections and propose protist and helminth candidates, chosen on the basis of several criteria, to test as possible therapy for selected human diseases. Previously, scientists sometimes resorted to infecting themselves or colleagues with parasites, usually to assess the pathogenicity and obtain insight into the life cycles of the parasites, host specificity, and epidemiology. However, with recent research addressing the possible beneficial impact of intestinal helminths on a range of immune-mediated diseases in humans, these studies offer valuable information, although many are now considered unethical owing to a lack of experimental oversight and informed consent. Here, we critically review cases in which humans were deliberately infected with parasites. Moreover, we summarize the contribution of (self-) infections and propose protist and helminth candidates, chosen on the basis of several criteria, to test as possible therapy for selected human diseases. (en)
Title	(Self-) infections with parasites: re-interpretations for the present (Self-) infections with parasites: re-interpretations for the present (en)
skos:prefLabel	(Self-) infections with parasites: re-interpretations for the present (Self-) infections with parasites: re-interpretations for the present (en)
skos:notation	RIV/60077344:_____/14:00435095!RIV15-GA0-60077344
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GAP506/12/1632)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Scholz, Tomáš Lukeš, Julius Kuchta, Roman Pomajbíková, Kateřina
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biologické centrum AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	44315
http://linked.open...ai/riv/idVysledku	RIV/60077344:_____/14:00435095
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	self-infection; volunteers; protists; helminths; autoimmune diseases; helminth therapy (en)
http://linked.open.../riv/klicoveSlovo	helminths helminth therapy self-infection autoimmune diseases volunteers protists
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[F8597DCB83C2]
http://linked.open...i/riv/nazevZdroje	Trends in Parasitology
http://linked.open...in/vavai/riv/obor	EG
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	From fish to man and from water to the earth: evolutionary history of tapeworms parasitizing tetrapodes (Cestoda: Diphyllobothriidea)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	30
http://linked.open...iv/tvurceVysledku	Lukeš, Julius Scholz, Tomáš Kuchta, Roman Pomajbíková, Kateřina
http://linked.open...ain/vavai/riv/wos	000340305300004
issn	1471-4922
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.pt.2014.06.005

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