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Description
  • Protein-sacharidové interakce se podílejí na vztazích mezi přenašeči a patogeny/parazity. Jeden z nejdůležitějších znaků jejich uplatnění v imunitní odpovědi na patogenní agens je stimulace jejich vazebných aktivit sáním krve nebo infekcí klíšťat patogenním agens. V přehledové kapitole je diskutován vzrůstající počet důkazů o existenci protein-sacharidových interakcí mezi klíštěcími tkáněmi a patogeny. Příštím cílem je úplné vysvětlení jejich biologické úlohy a významu v systémech klíště-patogen a z něho vycházející návrhy na trans-blocking strategii pro prevenci přenosu/šíření patogenů klíšťaty. V důsledku absence poznatků z oblasti klíštěcích lektinů a protein-sacharidových interakcí jsou předmětem sdělení zejména výsledky dosažené výzkumnou skupinou Parazitologického ústavu v Českých Budějovicích (Česká republika). (cs)
  • Protein-carbohydrate interactions are known to participate in vector-pathogen/parasite relationships. One of the most important issues implicating lectins in immune responses to pathogens is inducibility/upregulation of their binding activities after blood-feeding or pathogen invasion. With the increasing evidence of the existence of protein-carbohydrate interactions between tick tissues and pathogens, which are discussed in this review, the next goal is to elucidate their biological roles and significance in tick-pathogen relationships and to design potential disease-transmission-blocking strategies. Because of the lack of published data on tick lectins, most results are based on the research results of the Tick Lectin Group at the Institute of Parasitology, České Budějovice, Czech Republic.
  • Protein-carbohydrate interactions are known to participate in vector-pathogen/parasite relationships. One of the most important issues implicating lectins in immune responses to pathogens is inducibility/upregulation of their binding activities after blood-feeding or pathogen invasion. With the increasing evidence of the existence of protein-carbohydrate interactions between tick tissues and pathogens, which are discussed in this review, the next goal is to elucidate their biological roles and significance in tick-pathogen relationships and to design potential disease-transmission-blocking strategies. Because of the lack of published data on tick lectins, most results are based on the research results of the Tick Lectin Group at the Institute of Parasitology, České Budějovice, Czech Republic. (en)
Title
  • Tick lectins and fibrinogen-related proteins
  • Lektiny a fibrinogenu podobné proteiny klíšťat (cs)
  • Tick lectins and fibrinogen-related proteins (en)
skos:prefLabel
  • Tick lectins and fibrinogen-related proteins
  • Lektiny a fibrinogenu podobné proteiny klíšťat (cs)
  • Tick lectins and fibrinogen-related proteins (en)
skos:notation
  • RIV/60077344:_____/08:00319417!RIV09-GA0-60077344
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA206/04/0520), P(GA524/06/1479), P(IAA6022001), P(LC06009), Z(AV0Z60220518)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 400032
http://linked.open...ai/riv/idVysledku
  • RIV/60077344:_____/08:00319417
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • lectin; fibrinogen-related protein; protein-saccharide interaction (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [8B11235634C8]
http://linked.open...i/riv/mistoVydani
  • Cambridge
http://linked.open...i/riv/nazevZdroje
  • Ticks: Biology, Disease and Control
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Grubhoffer, Libor
  • Kovář, Vojtěch
  • Oliver, J. H. jr.
  • Rudenko, Natalia
  • Hajdušek, Ondřej
  • Hypša, Václav
  • Rego, Ryan O. M.
http://linked.open...n/vavai/riv/zamer
number of pages
http://purl.org/ne...btex#hasPublisher
  • Cambridge University Press
https://schema.org/isbn
  • 978-0-521-86761-0
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