About: Screening for acetylcholinesterase inhibitory activity in cyanobacteria of the genus Nostoc

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Fifty-four cyanobacterial strains of the genus Nostoc from different habitats were screened for acetylcholinesterase inhibitory activity. Water-methanolic extracts from freeze-dried biomasses were tested for inhibitory activity using Ellman's spectrophotometric method. Acetylcholinesterase inhibitory activity higher than 90% was found in the crude extracts of Nostoc sp. str. Lukesova 27/97 and Nostoc ellipsosporum Rabenh. str. Lukesova 51/91. Extracts from Nostoc ellipsosporum str. Lukesova 52/91 and Nostoc linckia f. muscorum (Ag.) Elenk. str. Gromov, 1988, CALU-980 inhibited AChE activity by 84.9% and 65.3% respectively. Moderate AChE inhibitory activity (29.1-37.5%) was found in extracts of Nostoc linckia Roth. str. Gromov, 1962/10, CALU-129, Nostoc muscorum Ag. str. Lukesova 127/97, Nostoc sp. str. Lhotsky, CALU-327 and Nostoc sp. str. Gromov, CALU-998. Extracts from another seven strains showed weak anti-AChE activities. The active component responsible for acetylcholinesterase inhibition wa Fifty-four cyanobacterial strains of the genus Nostoc from different habitats were screened for acetylcholinesterase inhibitory activity. Water-methanolic extracts from freeze-dried biomasses were tested for inhibitory activity using Ellman's spectrophotometric method. Acetylcholinesterase inhibitory activity higher than 90% was found in the crude extracts of Nostoc sp. str. Lukesova 27/97 and Nostoc ellipsosporum Rabenh. str. Lukesova 51/91. Extracts from Nostoc ellipsosporum str. Lukesova 52/91 and Nostoc linckia f. muscorum (Ag.) Elenk. str. Gromov, 1988, CALU-980 inhibited AChE activity by 84.9% and 65.3% respectively. Moderate AChE inhibitory activity (29.1-37.5%) was found in extracts of Nostoc linckia Roth. str. Gromov, 1962/10, CALU-129, Nostoc muscorum Ag. str. Lukesova 127/97, Nostoc sp. str. Lhotsky, CALU-327 and Nostoc sp. str. Gromov, CALU-998. Extracts from another seven strains showed weak anti-AChE activities. The active component responsible for acetylcholinesterase inhibition wa (en)
Title	Screening for acetylcholinesterase inhibitory activity in cyanobacteria of the genus Nostoc Screening for acetylcholinesterase inhibitory activity in cyanobacteria of the genus Nostoc (en)
skos:prefLabel	Screening for acetylcholinesterase inhibitory activity in cyanobacteria of the genus Nostoc Screening for acetylcholinesterase inhibitory activity in cyanobacteria of the genus Nostoc (en)
skos:notation	RIV/60076658:12640/09:00010059!RIV10-MSM-12640___
http://linked.open...avai/riv/aktivita	P V Z
http://linked.open...avai/riv/aktivity	P(ME 874), V, Z(AV0Z50200510), Z(AV0Z60660521)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Štys, Dalibor Kopecký, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Jihočeská univerzita v Českých Budějovicích / Ústav fyzikální biologie
http://linked.open...dnocenehoVysledku	340397
http://linked.open...ai/riv/idVysledku	RIV/60076658:12640/09:00010059
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Acetylcholinesterase; Alzheimer's disease; bioactivity; inhibitors; microalgae; Nostoc CHOLINESTERASE INHIBITOR; MEDICINAL-PLANTS; ANABAENA (en)
http://linked.open.../riv/klicoveSlovo	inhibitors Acetylcholinesterase bioactivity Alzheimer's disease microalgae ANABAENA MEDICINAL-PLANTS Nostoc CHOLINESTERASE INHIBITOR
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[51F937C482B0]
http://linked.open...i/riv/nazevZdroje	Journal of Enzyme Inhibition and Medicinal Chemistry
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	http://linked.opendata.cz/resource/domain/vavai/projekt/ME%20874
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	24
http://linked.open...iv/tvurceVysledku	Kopecký, Jiří Štys, Dalibor Lukesova, Alena Zelík, Petr Voloshko, Ludmila N
http://linked.open...ain/vavai/riv/wos	000264203100028
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology Relationships between the structure and function of decomposer food web in soil
issn	1475-6366
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	12640
is http://linked.open...avai/riv/vysledek of	Screening for acetylcholinesterase inhibitory activity in cyanobacteria of the genus Nostoc Screening for acetylcholinesterase inhibitory activity in cyanobacteria of the genus Nostoc Screening for acetylcholinesterase inhibitory activity in cyanobacteria of the genus Nostoc Screening for acetylcholinesterase inhibitory activity in cyanobacteria of the genus Nostoc

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