About: Protective Roles of Calcium Channel Blocker Against Cadmium-Induced Physiological Stress in Freshwater Teleost Oncorhynchus mykiss     Goto   Sponge   NotDistinct   Permalink

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  • The roles of Verapamil on Cd-induced physiological stress in teleost Oncorhynchus mykiss were investigated in this study. Forty-eight juvenile rainbow trout were divided randomly into 4 groups, i.e., control group, VRP group (100 mýg/L VRP), Cd group (50 mýg/L Cd2+) and VRP+Cd group (100 mýg/L VRP + 50 mýg/L Cd2+). After one week exposure, oxidative stress indices and antioxidant parameters were measured in gill and liver tissues and the behavioral changes were recorded. Compared with the control, Cd-induced stress was apparent as reflected by a serious oxidative stress in fish tissues, and abnormal behaviors observed. In the VRP+Cd group, the antioxidant defense system of fish returned to the control level and the fish behavioral abnormalism markedly decreased. The results suggested that VRP could reduce the Cd-induced physiological stress in fish and provided further evidence that Cd2+ uptake through Ca2+ transport pathways in freshwater teleost.
  • The roles of Verapamil on Cd-induced physiological stress in teleost Oncorhynchus mykiss were investigated in this study. Forty-eight juvenile rainbow trout were divided randomly into 4 groups, i.e., control group, VRP group (100 mýg/L VRP), Cd group (50 mýg/L Cd2+) and VRP+Cd group (100 mýg/L VRP + 50 mýg/L Cd2+). After one week exposure, oxidative stress indices and antioxidant parameters were measured in gill and liver tissues and the behavioral changes were recorded. Compared with the control, Cd-induced stress was apparent as reflected by a serious oxidative stress in fish tissues, and abnormal behaviors observed. In the VRP+Cd group, the antioxidant defense system of fish returned to the control level and the fish behavioral abnormalism markedly decreased. The results suggested that VRP could reduce the Cd-induced physiological stress in fish and provided further evidence that Cd2+ uptake through Ca2+ transport pathways in freshwater teleost. (en)
Title
  • Protective Roles of Calcium Channel Blocker Against Cadmium-Induced Physiological Stress in Freshwater Teleost Oncorhynchus mykiss
  • Protective Roles of Calcium Channel Blocker Against Cadmium-Induced Physiological Stress in Freshwater Teleost Oncorhynchus mykiss (en)
skos:prefLabel
  • Protective Roles of Calcium Channel Blocker Against Cadmium-Induced Physiological Stress in Freshwater Teleost Oncorhynchus mykiss
  • Protective Roles of Calcium Channel Blocker Against Cadmium-Induced Physiological Stress in Freshwater Teleost Oncorhynchus mykiss (en)
skos:notation
  • RIV/60076658:12520/11:43881327!RIV12-MZP-12520___
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  • P(ED2.1.00/01.0024), P(SP/2E7/229/07), S
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  • 1-4
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  • 224809
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  • RIV/60076658:12520/11:43881327
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  • Protective effects; Antioxidant response; Behavior alteration; Fish; Verapamil (en)
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  • NL - Nizozemsko
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  • [29C811CF75B8]
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  • Water Air and Soil Pollution
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  • 220
http://linked.open...iv/tvurceVysledku
  • Li, Ping
  • Li, Zhihua
  • Randák, Tomáš
http://linked.open...ain/vavai/riv/wos
  • 000293783700027
issn
  • 0049-6979
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s11270-011-0754-4
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  • 12520
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