About: Use of hematological and plasma biochemical parameters to assess the chronic effects of a fungicide propiconazole on a freshwater teleost     Goto   Sponge   NotDistinct   Permalink

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  • The chronic effects of propiconazole, a triazole fungicide present in aquatic environment, on hematology of rainbow trout were investigated in this study. Fish were exposed at various concentrations of PCZ (0.2, 50 and 500 mu mg L/1) for 7, 20 and 30 d. Multiple biomarkers were measured, including hematological indices (hemoglobin concentration, red blood cells count, hematocrit, leukocyte count, mean erythrocyte hemoglobin, mean erythrocyte volume and mean color concentration) and plasma biochemical parameters (ammonia, glucose, total proteins, creatine kinase, lactate dehydrogenase, alanine aminotransferase and aspartate aminotransferase). Through principal component analysis and integrated biomarker response assessment, influence extent induced by PCZ-stress of each test group was distinguished. The results of this study indicate that chronic exposure of PCZ has altered multiple physiological indices in fish hematology and CK activity may be an early biomarker of PCZ toxicity.
  • The chronic effects of propiconazole, a triazole fungicide present in aquatic environment, on hematology of rainbow trout were investigated in this study. Fish were exposed at various concentrations of PCZ (0.2, 50 and 500 mu mg L/1) for 7, 20 and 30 d. Multiple biomarkers were measured, including hematological indices (hemoglobin concentration, red blood cells count, hematocrit, leukocyte count, mean erythrocyte hemoglobin, mean erythrocyte volume and mean color concentration) and plasma biochemical parameters (ammonia, glucose, total proteins, creatine kinase, lactate dehydrogenase, alanine aminotransferase and aspartate aminotransferase). Through principal component analysis and integrated biomarker response assessment, influence extent induced by PCZ-stress of each test group was distinguished. The results of this study indicate that chronic exposure of PCZ has altered multiple physiological indices in fish hematology and CK activity may be an early biomarker of PCZ toxicity. (en)
Title
  • Use of hematological and plasma biochemical parameters to assess the chronic effects of a fungicide propiconazole on a freshwater teleost
  • Use of hematological and plasma biochemical parameters to assess the chronic effects of a fungicide propiconazole on a freshwater teleost (en)
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  • Use of hematological and plasma biochemical parameters to assess the chronic effects of a fungicide propiconazole on a freshwater teleost
  • Use of hematological and plasma biochemical parameters to assess the chronic effects of a fungicide propiconazole on a freshwater teleost (en)
skos:notation
  • RIV/60076658:12520/11:43873083!RIV12-MZP-12520___
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  • P(ED2.1.00/01.0024), P(SP/2E7/229/07), S
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  • 4
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  • 237203
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  • RIV/60076658:12520/11:43873083
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  • Two-way ANOVA; Principal component analysis; Integrated biomarker response; Hematology; Propiconazole; Fish (en)
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  • GB - Spojené království Velké Británie a Severního Irska
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  • [EEA03EB973BB]
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  • Chemosphere
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  • 83
http://linked.open...iv/tvurceVysledku
  • Grabic, Roman
  • Kolářová, Jitka
  • Li, Ping
  • Li, Zhihua
  • Randák, Tomáš
  • Velíšek, Josef
http://linked.open...ain/vavai/riv/wos
  • 000289879500025
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  • 0045-6535
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  • 10.1016/j.chemosphere.2010.12.024
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  • 12520
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