About: Trypanosoma brucei solanesyl-diphosphate synthase localizes to themitochondrion

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Trypanosoma brucei solanesyl-diphosphate synthase localizes to themitochondrion Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Polyprenyl-diphosphate synthase is a key enzyme in the biosynthesis of ubiquinone, a molecule considered essential for a typical eukaryotic cell. Its orthologue in the American stercorarian flagellate Trypanosoma cruzi, solanesyl diphosphate synthase, has been previously localized into the glycosomes. We wondered whether this unique cellular localization is shared by other trypanosome species. Using digitonin permeabilization, immunofluorescence and in situ tagging techniques, we show that in Trypanosoma brucei, the African salivarian flagellate, the enzyme localizes to the mitochondrion. Polyprenyl-diphosphate synthase is a key enzyme in the biosynthesis of ubiquinone, a molecule considered essential for a typical eukaryotic cell. Its orthologue in the American stercorarian flagellate Trypanosoma cruzi, solanesyl diphosphate synthase, has been previously localized into the glycosomes. We wondered whether this unique cellular localization is shared by other trypanosome species. Using digitonin permeabilization, immunofluorescence and in situ tagging techniques, we show that in Trypanosoma brucei, the African salivarian flagellate, the enzyme localizes to the mitochondrion. (en)
Title	Trypanosoma brucei solanesyl-diphosphate synthase localizes to themitochondrion Trypanosoma brucei solanesyl-diphosphate synthase localizes to themitochondrion (en)
skos:prefLabel	Trypanosoma brucei solanesyl-diphosphate synthase localizes to themitochondrion Trypanosoma brucei solanesyl-diphosphate synthase localizes to themitochondrion (en)
skos:notation	RIV/60076658:12310/12:43883297!RIV13-MSM-12310___
http://linked.open...avai/predkladatel	Přírodovědecká fakulta
http://linked.open...avai/riv/aktivita	I P V
http://linked.open...avai/riv/aktivity	I, P(GAP305/11/2179), V
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Lukeš, Julius
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Jihočeská univerzita v Českých Budějovicích / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	175276
http://linked.open...ai/riv/idVysledku	RIV/60076658:12310/12:43883297
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	In situ tagging; Digitonin permeabilization; Solanesyl-diphosphatesynthase; Ubiquinone; Sleeping sickness; Trypanosoma brucei; GROWTH; INHIBITORS; CRUZI; PROTEINS; BIOSYNTHESIS; UBIQUINONE; X-RAY; COENZYME-Q; LIPOPHILIC BISPHOSPHONATES (en)
http://linked.open.../riv/klicoveSlovo	COENZYME-Q CRUZI Digitonin permeabilization In situ tagging LIPOPHILIC BISPHOSPHONATES Sleeping sickness Solanesyl-diphosphatesynthase Trypanosoma brucei UBIQUINONE Ubiquinone BIOSYNTHESIS GROWTH X-RAY INHIBITORS PROTEINS
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[733105A4E9D8]
http://linked.open...i/riv/nazevZdroje	MOLECULAR AND BIOCHEMICAL PARASITOLOGY
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Characterization of Fe-S cluster assembly in Trypanosoma brucei
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	183
http://linked.open...iv/tvurceVysledku	Lukeš, Julius Bontempi, Esteban J. Lai, De-Hua
http://linked.open...ain/vavai/riv/wos	000303845400011
issn	0166-6851
number of pages	4 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.molbiopara.2012.02.011
http://localhost/t...ganizacniJednotka	12310
is http://linked.open...avai/riv/vysledek of	Trypanosoma brucei solanesyl-diphosphate synthase localizes to themitochondrion

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 75 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software