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  • Problem of tissue perfusion reconstruction is quite challenging for the biomechanical and biomedical research. It is desirable to find accurately parts of the tissue with an insufficient blood supply, to localize anomalies in the blood micro-circulation and to quantify locally the perfusion efficiency. To cope with the complexity of the perfusion trees, we use a combination of 3D and 1D fluid dynamics for large and medium vessels, respectively, whereas Darcy flow %220D%22 models are used to describe blood redistribution in the parenchyma and smaller vessels. In this paper we describe a simplified model on which we test the modeling of the perfusion and tracer transport.The computed perfusion velocities are employed to simulate the dynamic perfusion test. The output of such a simulation can be compared with the clinical CT data scans of the perfusion tests.
  • Problem of tissue perfusion reconstruction is quite challenging for the biomechanical and biomedical research. It is desirable to find accurately parts of the tissue with an insufficient blood supply, to localize anomalies in the blood micro-circulation and to quantify locally the perfusion efficiency. To cope with the complexity of the perfusion trees, we use a combination of 3D and 1D fluid dynamics for large and medium vessels, respectively, whereas Darcy flow %220D%22 models are used to describe blood redistribution in the parenchyma and smaller vessels. In this paper we describe a simplified model on which we test the modeling of the perfusion and tracer transport.The computed perfusion velocities are employed to simulate the dynamic perfusion test. The output of such a simulation can be compared with the clinical CT data scans of the perfusion tests. (en)
Title
  • Modeling dynamic CT perfusion test using multicompartment models
  • Modeling dynamic CT perfusion test using multicompartment models (en)
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  • Modeling dynamic CT perfusion test using multicompartment models
  • Modeling dynamic CT perfusion test using multicompartment models (en)
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  • RIV/49777513:23520/12:43916279!RIV13-GA0-23520___
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  • P(ED1.1.00/02.0090), P(GA106/09/0740), P(NT13326)
http://linked.open...vai/riv/dodaniDat
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  • 150994
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  • RIV/49777513:23520/12:43916279
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  • blood perfusion, Darcy flow, multi-compartment model, tracer transport, hierarchical modeling (en)
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  • [45957C06995B]
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  • Bublík, Ondřej
  • Jonášová, Alena
  • Lukeš, Vladimír
  • Rohan, Eduard
  • Vimmr, Jan
http://localhost/t...ganizacniJednotka
  • 23520
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