About: Computational homogenization of tissue parenchyma using layer-wise decomposition

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The mathematical model of perfusion through different hierarchies of tissue parenchyma can be derived using the asymptotic homogenization technique which is applied to the Darcy flow problem in the multi-compartment medium with a dual porosity. This approach gives us the tool for decomposition of a 3D volume into a finite number of homogenized 2D layers coupled together by conditions governing the fluid exchange between them. The layer-wise decomposition allows us to approximate the hierarchical structure of the perfusion tree by several homogenized layers with distinct material properties and topology of the underlying microstructure. The tissue parenchyma can be considered as a structure consisting of small arteries and veins connected together by microvessels and capillaries. In the model, the arteries and veins are represented by two disconnected channels. Fluid can flow between these two primary porosities through the matrix representing the dual porosity where the permeability is decreasing with the size of the microstructure. The dual porosity corresponds to a network of the smallest vessels in the perfusion hierarchy. The mathematical model of perfusion through different hierarchies of tissue parenchyma can be derived using the asymptotic homogenization technique which is applied to the Darcy flow problem in the multi-compartment medium with a dual porosity. This approach gives us the tool for decomposition of a 3D volume into a finite number of homogenized 2D layers coupled together by conditions governing the fluid exchange between them. The layer-wise decomposition allows us to approximate the hierarchical structure of the perfusion tree by several homogenized layers with distinct material properties and topology of the underlying microstructure. The tissue parenchyma can be considered as a structure consisting of small arteries and veins connected together by microvessels and capillaries. In the model, the arteries and veins are represented by two disconnected channels. Fluid can flow between these two primary porosities through the matrix representing the dual porosity where the permeability is decreasing with the size of the microstructure. The dual porosity corresponds to a network of the smallest vessels in the perfusion hierarchy. (en)
Title	Computational homogenization of tissue parenchyma using layer-wise decomposition Computational homogenization of tissue parenchyma using layer-wise decomposition (en)
skos:prefLabel	Computational homogenization of tissue parenchyma using layer-wise decomposition Computational homogenization of tissue parenchyma using layer-wise decomposition (en)
skos:notation	RIV/49777513:23520/12:43916259!RIV13-GA0-23520___
http://linked.open...avai/predkladatel	Fakulta aplikovaných věd
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0090), P(GA106/09/0740)
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Rohan, Eduard Lukeš, Vladimír
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Západočeská univerzita v Plzni / Fakulta aplikovaných věd
http://linked.open...dnocenehoVysledku	128277
http://linked.open...ai/riv/idVysledku	RIV/49777513:23520/12:43916259
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	mutliscale modeling; porous media; perfusion; homogenization (en)
http://linked.open.../riv/klicoveSlovo	perfusion homogenization porous media mutliscale modeling
http://linked.open...ontrolniKodProRIV	[7CAAB8F0B69A]
http://linked.open...in/vavai/riv/obor	BI
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Microstructure oriented hierarchical modeling of brain perfusion for CT based cerebral blood flow evaluation NTIS - New Technologies for Information Society
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Lukeš, Vladimír Rohan, Eduard
http://localhost/t...ganizacniJednotka	23520

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