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  • Silanization of substrates with Si-OH groups on the surface is one of the methods currently used in engineering of special materials. Such modification allows e.g. immobilisation of drugs on different surfaces. In this study, tetracycline was successfully immobilised through silanization reactions on silica nanofibres with Si-OH groups. The immobilisation of tetracycline was confirmed by fluorescent microscopy (Olympus BX51, camera DP 72) and it was also proved by their antibacterial effect on selected bacterial strains. The silanization reactions were performed in different solvents. The best results were obtained when the silanization proceeded in water with a rinse in acetic acid.
  • Silanization of substrates with Si-OH groups on the surface is one of the methods currently used in engineering of special materials. Such modification allows e.g. immobilisation of drugs on different surfaces. In this study, tetracycline was successfully immobilised through silanization reactions on silica nanofibres with Si-OH groups. The immobilisation of tetracycline was confirmed by fluorescent microscopy (Olympus BX51, camera DP 72) and it was also proved by their antibacterial effect on selected bacterial strains. The silanization reactions were performed in different solvents. The best results were obtained when the silanization proceeded in water with a rinse in acetic acid. (en)
Title
  • Immobilisation of antibiotic tetracycline on silica nanofibers
  • Immobilisation of antibiotic tetracycline on silica nanofibers (en)
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  • Immobilisation of antibiotic tetracycline on silica nanofibers
  • Immobilisation of antibiotic tetracycline on silica nanofibers (en)
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  • RIV/46747885:24220/12:#0002230!RIV13-MSM-24220___
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  • 140541
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  • RIV/46747885:24220/12:#0002230
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  • nanofibre; silanization; organosilane; immobilisation; tetracycline; antibacterial effect (en)
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  • SK - Slovenská republika
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  • [F69A657F50EF]
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  • 19
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  • Šlamborová, Irena
  • Zajícová, Veronika
  • Exnar, Petr
  • Karpíšková, Jana
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  • 1335-0617
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