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| Description
| - In recently, there has been a great interest in natural antioxidants as bioactive components of food, nutraceuticals or potential drugs against several diseases. In our study, 88 extracts from various parts of plants from European Asteraceae and Cichoriaceae were assayed for radical scavenging activity by means of DPPH (1,1-diphenyl-2-picryl hydrazyl radical) test using the SIA (Sequential injection analysis) method developed for this purpose in our laboratory. DPPH radical scavenging activity of all tested plant extracts was evaluated according to the IC50 parameter. 29 extracts exhibited IC50 value lower than 0.1 mg/mL. The leaves of Leuzea carthamoides (IC50 Ľ 0.046 mg/mL) were chosen as the most promising sample for a subsequent phytochemical study, which resulted in isolation of seven natural compounds, namely, 40,5,7-trihydroxy-6-methoxyflavone (hispidulin) (1), 5, 7, 30, 40- tetrahydroxyflavanone (eriodictyol) (2), 30,40,5,7-pentahydroxy-6-methoxyflavonol (patuletin) (3), eriodictyol-7-b-glucop
- In recently, there has been a great interest in natural antioxidants as bioactive components of food, nutraceuticals or potential drugs against several diseases. In our study, 88 extracts from various parts of plants from European Asteraceae and Cichoriaceae were assayed for radical scavenging activity by means of DPPH (1,1-diphenyl-2-picryl hydrazyl radical) test using the SIA (Sequential injection analysis) method developed for this purpose in our laboratory. DPPH radical scavenging activity of all tested plant extracts was evaluated according to the IC50 parameter. 29 extracts exhibited IC50 value lower than 0.1 mg/mL. The leaves of Leuzea carthamoides (IC50 Ľ 0.046 mg/mL) were chosen as the most promising sample for a subsequent phytochemical study, which resulted in isolation of seven natural compounds, namely, 40,5,7-trihydroxy-6-methoxyflavone (hispidulin) (1), 5, 7, 30, 40- tetrahydroxyflavanone (eriodictyol) (2), 30,40,5,7-pentahydroxy-6-methoxyflavonol (patuletin) (3), eriodictyol-7-b-glucop (en)
- V současnosti je velký zájem o přírodní antioxidanty jako bioaktivní komponenty jída, nutraceutic či potenciálních léků proti některým nemocem. V naší studii bylo změřeno 88 extraktů z rozličných částí rostlin z evropské Asteraceae a Cichoriaceae pro aktivitu vychytávání radikálů způsobem DPPH (1,1-difenyl-2-pikryl hydrazyl radikal) testu pomocí SIA (Sekvenční Injekční analýza) metody vyvinuté pro tento účel v naš laboratoři. DPPH vychytávací radikálová aktivita testovaných rostlinných extraktů byla zhodnocena pomocí parametru IC50. 29 extraktů prokázalo IC50 hodnoty nižší než 0.1 mg/mL. Listy Leuzea carthamoides (IC50 L 0.046 mg/mL) byly vybrány jako nejslibnější vzorky pro násednou fytochemickou studii, jejímž výsledkem byla izolace sedmi přírodních sloučenin, jměnovitě - 40,5,7-trihydroxy-6-methoxyflavone (hispidulin) (1), 5, 7, 30, 40- tetrahydroxyflavanone (eriodiktyol) (2), 30,40,5,7-pentahydroxy-6-methoxyflavonol (patuletin) (3), eriodictyol-7-b-glucopyranoside (4), 6-hydroxykaempferol-7-O-(600 (cs)
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| Title
| - Evaluation of natural antioxidants of leuzea carthamoides as a result of screening study of 88 plant extracts from the european asteraceae and cichoriaceae
- Zhodnocení přírodních antioxidantů leuzea carthamoides jako výsledek skríningové studie extraktů 88 rostlin z evropské asteraceae a cichoriaceae (cs)
- Evaluation of natural antioxidants of leuzea carthamoides as a result of screening study of 88 plant extracts from the european asteraceae and cichoriaceae (en)
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| skos:prefLabel
| - Evaluation of natural antioxidants of leuzea carthamoides as a result of screening study of 88 plant extracts from the european asteraceae and cichoriaceae
- Zhodnocení přírodních antioxidantů leuzea carthamoides jako výsledek skríningové studie extraktů 88 rostlin z evropské asteraceae a cichoriaceae (cs)
- Evaluation of natural antioxidants of leuzea carthamoides as a result of screening study of 88 plant extracts from the european asteraceae and cichoriaceae (en)
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| skos:notation
| - RIV/44555601:13440/08:00004262!RIV09-MSM-13440___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/44555601:13440/08:00004262
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Antioxidant; Leuzea carthamoides; DPPH; FRAP; plant; flavonoid; phenolic acid; free radical (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Journal of Enzyme Inhibition and Medicinal Chemistry
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...iv/tvurceVysledku
| - Kuča, Kamil
- Kuneš, Jiří
- Jun, Daniel
- Opletal, Lubomír
- Jahodář, Luděk
- Červenka, František
- Řeháková, Zuzana
- Brojerová, Eliška
- Kubíková, Kateřina
- Koleckar, Vít
- Polásek, Miroslav
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| http://linked.open...ain/vavai/riv/wos
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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