About: Cisplatin-resistant prostate cancer model: Differences in antioxidant system, apoptosis and cell cycle

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About: Cisplatin-resistant prostate cancer model: Differences in antioxidant system, apoptosis and cell cycle Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Differences in the antioxidant system, apoptotic mechanism and in cell cycle between prostatic cell lines could partially elucidate the development of cisplatin resistance. The aim of this study was to identify the most characteristic parameter for a particular cell line and/or a particular cisplatin treatment using a general regression model and to assess whether it is possible to use measured parameters as markers of cisplatin resistance. This study integrates the results of viability, antioxidant, flow cytometric and quantitative PCR assays in order to characterize the resistance of prostate cancer to cisplatin. Differences in the antioxidant system, apoptotic mechanism and in cell cycle between prostatic cell lines could partially elucidate the development of cisplatin resistance. The aim of this study was to identify the most characteristic parameter for a particular cell line and/or a particular cisplatin treatment using a general regression model and to assess whether it is possible to use measured parameters as markers of cisplatin resistance. This study integrates the results of viability, antioxidant, flow cytometric and quantitative PCR assays in order to characterize the resistance of prostate cancer to cisplatin. (en)
Title	Cisplatin-resistant prostate cancer model: Differences in antioxidant system, apoptosis and cell cycle Cisplatin-resistant prostate cancer model: Differences in antioxidant system, apoptosis and cell cycle (en)
skos:prefLabel	Cisplatin-resistant prostate cancer model: Differences in antioxidant system, apoptosis and cell cycle Cisplatin-resistant prostate cancer model: Differences in antioxidant system, apoptosis and cell cycle (en)
skos:notation	RIV/00216305:26620/14:PU107963!RIV15-MSM-26620___
http://linked.open...avai/riv/aktivita	I P V
http://linked.open...avai/riv/aktivity	I, P(ED1.1.00/02.0068), P(EE2.3.20.0183), P(GAP301/10/0356), V
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Gumulec, Jaromír Babula, Petr Adam, Vojtěch Masařík, Michal Kizek, René Ruttkay-Nedecký, Branislav Balvan, Jan Polanská, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Vysoké učení technické v Brně / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	7356
http://linked.open...ai/riv/idVysledku	RIV/00216305:26620/14:PU107963
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	prostate cancer, cell cycle, resistance, cisplatin, oxidative stress, (en)
http://linked.open.../riv/klicoveSlovo	prostate cancer resistance cisplatin oxidative stress cell cycle
http://linked.open...odStatuVydavatele	GR - Řecká republika
http://linked.open...ontrolniKodProRIV	[1F15499C6DEC]
http://linked.open...i/riv/nazevZdroje	INTERNATIONAL JOURNAL OF ONCOLOGY
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	14 (xsd:int)
http://linked.open...vavai/riv/projekt	Center of Experimental Biomedicine Central european institute of technology Study of contribution of different DNA-damaging mechanisms to toxicity of cytostatics to human chemosensitive and chemoresistant neuroblastomas
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	44
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Babula, Petr Gumulec, Jaromír Kizek, René Knopfová, Lucia Masařík, Michal Stiborová, Marie Sztalmachová, Markéta Tanhäuserová, Veronika Ruttkay-Nedecký, Branislav Balvan, Jan Raudenská, Martina Hudcová, Kristýna Polanská, Hana
issn	1019-6439
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	26620

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